ID   DN7A_SULID              Reviewed;          64 AA.
AC   D2PHL8;
DT   15-MAR-2017, integrated into UniProtKB/Swiss-Prot.
DT   02-MAR-2010, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=DNA-binding protein 7a {ECO:0000305};
DE   AltName: Full=7 kDa DNA-binding protein a {ECO:0000305};
DE   AltName: Full=Sis7a {ECO:0000303|PubMed:27853299};
GN   OrderedLocusNames=LD85_0770 {ECO:0000312|EMBL:ADB86496.1};
OS   Sulfolobus islandicus (strain L.D.8.5 / Lassen #2).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=425944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L.D.8.5 / Lassen #2;
RX   PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA   Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT   "Biogeography of the Sulfolobus islandicus pan-genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
RN   [2]
RP   DNA-BINDING, BIOPHYSICOCHEMICAL PROPERTIES, SUBUNIT, SUBCELLULAR LOCATION,
RP   AND NOMENCLATURE.
RX   PubMed=27853299; DOI=10.1038/srep37274;
RA   Kalichuk V., Behar G., Renodon-Corniere A., Danovski G., Obal G.,
RA   Barbet J., Mouratou B., Pecorari F.;
RT   "The archaeal '7 kDa DNA-binding' proteins: extended characterization of an
RT   old gifted family.";
RL   Sci. Rep. 6:37274-37274(2016).
CC   -!- FUNCTION: Can constrain negative DNA supercoils. May be involved in
CC       maintaining the integrity of the genome at high temperature.
CC       {ECO:0000250|UniProtKB:P61990}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Highly stable from pH 0 to pH 12. {ECO:0000269|PubMed:27853299};
CC       Temperature dependence:
CC         Hyperthermostable. {ECO:0000269|PubMed:27853299};
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:27853299}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27853299}.
CC   -!- SIMILARITY: Belongs to the 7 kDa DNA-binding/endoribonuclease P2
CC       family. {ECO:0000305}.
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DR   EMBL; CP001731; ADB86496.1; -; Genomic_DNA.
DR   RefSeq; WP_012713334.1; NC_013769.1.
DR   AlphaFoldDB; D2PHL8; -.
DR   SMR; D2PHL8; -.
DR   EnsemblBacteria; ADB86496; ADB86496; LD85_0770.
DR   GeneID; 7797411; -.
DR   GeneID; 7941705; -.
DR   GeneID; 8760595; -.
DR   KEGG; sii:LD85_0770; -.
DR   HOGENOM; CLU_2929990_0_0_2; -.
DR   OMA; MATKIKF; -.
DR   Proteomes; UP000001404; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:InterPro.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR003212; DNA-bd_7kDa_arc.
DR   Pfam; PF02294; 7kD_DNA_binding; 1.
DR   PIRSF; PIRSF036912; Sac7; 1.
DR   SUPFAM; SSF54160; SSF54160; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; DNA-binding.
FT   CHAIN           1..64
FT                   /note="DNA-binding protein 7a"
FT                   /id="PRO_0000439050"
SQ   SEQUENCE   64 AA;  7309 MW;  0E57CD56FCCF91C8 CRC64;
     MTTVKFKYKG EEKQVDISKI KKVWRVGKMI SFTYDEGGGK TGRGAVSEKD APKELLQMLE
     KQKK