ID   DN7B_SULIH              Reviewed;          64 AA.
AC   F0NJT3;
DT   15-MAR-2017, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=DNA-binding protein 7b {ECO:0000305};
DE   AltName: Full=7 kDa DNA-binding protein b {ECO:0000305};
DE   AltName: Full=Sis7b {ECO:0000303|PubMed:27853299};
GN   OrderedLocusNames=SiH_0663 {ECO:0000312|EMBL:ADX82020.1};
OS   Sulfolobus islandicus (strain HVE10/4).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfolobus.
OX   NCBI_TaxID=930943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HVE10/4;
RX   PubMed=21278296; DOI=10.1128/jb.01487-10;
RA   Guo L., Brugger K., Liu C., Shah S.A., Zheng H., Zhu Y., Wang S.,
RA   Lillestol R.K., Chen L., Frank J., Prangishvili D., Paulin L., She Q.,
RA   Huang L., Garrett R.A.;
RT   "Genome analyses of icelandic strains of Sulfolobus islandicus, model
RT   organisms for genetic and virus-host interaction studies.";
RL   J. Bacteriol. 193:1672-1680(2011).
RN   [2]
RP   DNA-BINDING, BIOPHYSICOCHEMICAL PROPERTIES, SUBUNIT, SUBCELLULAR LOCATION,
RP   AND NOMENCLATURE.
RX   PubMed=27853299; DOI=10.1038/srep37274;
RA   Kalichuk V., Behar G., Renodon-Corniere A., Danovski G., Obal G.,
RA   Barbet J., Mouratou B., Pecorari F.;
RT   "The archaeal '7 kDa DNA-binding' proteins: extended characterization of an
RT   old gifted family.";
RL   Sci. Rep. 6:37274-37274(2016).
CC   -!- FUNCTION: Can constrain negative DNA supercoils. May be involved in
CC       maintaining the integrity of the genome at high temperature.
CC       {ECO:0000250|UniProtKB:P61990}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Highly stable from pH 0 to pH 12. {ECO:0000269|PubMed:27853299};
CC       Temperature dependence:
CC         Hyperthermostable. {ECO:0000269|PubMed:27853299};
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:27853299}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27853299}.
CC   -!- SIMILARITY: Belongs to the 7 kDa DNA-binding/endoribonuclease P2
CC       family. {ECO:0000305}.
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DR   EMBL; CP002426; ADX82020.1; -; Genomic_DNA.
DR   RefSeq; WP_014512200.1; NC_017275.1.
DR   AlphaFoldDB; F0NJT3; -.
DR   SMR; F0NJT3; -.
DR   EnsemblBacteria; ADX82020; ADX82020; SiH_0663.
DR   GeneID; 15297198; -.
DR   KEGG; sih:SiH_0663; -.
DR   HOGENOM; CLU_2929990_0_0_2; -.
DR   OMA; MATKIKF; -.
DR   Proteomes; UP000006395; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:InterPro.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR003212; DNA-bd_7kDa_arc.
DR   Pfam; PF02294; 7kD_DNA_binding; 1.
DR   SUPFAM; SSF54160; SSF54160; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; DNA-binding.
FT   CHAIN           1..64
FT                   /note="DNA-binding protein 7b"
FT                   /id="PRO_0000439051"
SQ   SEQUENCE   64 AA;  7297 MW;  D88CB466FCCF91D3 CRC64;
     MTTVKFKYKG EEKQVDTSKI KKVWRVGKMI SFTYDEGGGK TGRGAVSEKD APKELLQMLE
     KQKK