ID   DN7_METCR               Reviewed;          62 AA.
AC   F4FYY6;
DT   15-MAR-2017, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=DNA-binding protein 7 {ECO:0000305};
DE   AltName: Full=7 kDa DNA-binding protein {ECO:0000305};
DE   AltName: Full=Mcu7 {ECO:0000303|PubMed:27853299};
GN   OrderedLocusNames=Mcup_1453 {ECO:0000312|EMBL:AEB95556.1};
OS   Metallosphaera cuprina (strain Ar-4).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=1006006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ar-4;
RX   PubMed=21551305; DOI=10.1128/jb.05038-11;
RA   Liu L.J., You X.Y., Zheng H., Wang S., Jiang C.Y., Liu S.J.;
RT   "Complete genome sequence of Metallosphaera cuprina, a metal sulfide-
RT   oxidizing archaeon from a hot spring.";
RL   J. Bacteriol. 193:3387-3388(2011).
RN   [2]
RP   DNA-BINDING, BIOPHYSICOCHEMICAL PROPERTIES, SUBUNIT, SUBCELLULAR LOCATION,
RP   AND NOMENCLATURE.
RX   PubMed=27853299; DOI=10.1038/srep37274;
RA   Kalichuk V., Behar G., Renodon-Corniere A., Danovski G., Obal G.,
RA   Barbet J., Mouratou B., Pecorari F.;
RT   "The archaeal '7 kDa DNA-binding' proteins: extended characterization of an
RT   old gifted family.";
RL   Sci. Rep. 6:37274-37274(2016).
CC   -!- FUNCTION: Can constrain negative DNA supercoils. May be involved in
CC       maintaining the integrity of the genome at high temperature.
CC       {ECO:0000250|UniProtKB:P61990}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Highly stable from pH 0 to pH 12. {ECO:0000269|PubMed:27853299};
CC       Temperature dependence:
CC         Hyperthermostable. {ECO:0000269|PubMed:27853299};
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:27853299}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27853299}.
CC   -!- SIMILARITY: Belongs to the 7 kDa DNA-binding/endoribonuclease P2
CC       family. {ECO:0000305}.
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DR   EMBL; CP002656; AEB95556.1; -; Genomic_DNA.
DR   RefSeq; WP_013738054.1; NC_015435.1.
DR   AlphaFoldDB; F4FYY6; -.
DR   SMR; F4FYY6; -.
DR   EnsemblBacteria; AEB95556; AEB95556; Mcup_1453.
DR   GeneID; 10493642; -.
DR   KEGG; mcn:Mcup_1453; -.
DR   PATRIC; fig|1006006.8.peg.1448; -.
DR   eggNOG; arCOG05888; Archaea.
DR   HOGENOM; CLU_2929990_0_0_2; -.
DR   OMA; MATKIKF; -.
DR   OrthoDB; 128098at2157; -.
DR   Proteomes; UP000007812; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:InterPro.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR003212; DNA-bd_7kDa_arc.
DR   Pfam; PF02294; 7kD_DNA_binding; 1.
DR   SUPFAM; SSF54160; SSF54160; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; DNA-binding.
FT   CHAIN           1..62
FT                   /note="DNA-binding protein 7"
FT                   /id="PRO_0000439048"
SQ   SEQUENCE   62 AA;  6952 MW;  2BACB8289A94BF10 CRC64;
     MATKIKFKYK GQDLEVDISK VKKVWKVGKM VSFTYDDNGK TGRGAVSEKD APKELLSMIG
     KK