ID   DN7_METS5               Reviewed;          62 AA.
AC   A4YEA2;
DT   15-MAR-2017, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=DNA-binding protein 7 {ECO:0000305};
DE   AltName: Full=7 kDa DNA-binding protein {ECO:0000305};
DE   AltName: Full=Mse7 {ECO:0000303|PubMed:27853299};
GN   OrderedLocusNames=Msed_0579 {ECO:0000312|EMBL:ABP94754.1};
OS   Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS   / TH2).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=399549;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2;
RX   PubMed=18083856; DOI=10.1128/aem.02019-07;
RA   Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT   "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT   archaeon Metallosphaera sedula provides insights into bioleaching-
RT   associated metabolism.";
RL   Appl. Environ. Microbiol. 74:682-692(2008).
RN   [2]
RP   DNA-BINDING, BIOPHYSICOCHEMICAL PROPERTIES, SUBUNIT, SUBCELLULAR LOCATION,
RP   AND NOMENCLATURE.
RX   PubMed=27853299; DOI=10.1038/srep37274;
RA   Kalichuk V., Behar G., Renodon-Corniere A., Danovski G., Obal G.,
RA   Barbet J., Mouratou B., Pecorari F.;
RT   "The archaeal '7 kDa DNA-binding' proteins: extended characterization of an
RT   old gifted family.";
RL   Sci. Rep. 6:37274-37274(2016).
CC   -!- FUNCTION: Can constrain negative DNA supercoils. May be involved in
CC       maintaining the integrity of the genome at high temperature.
CC       {ECO:0000250|UniProtKB:P61990}.
CC   -!- BIOPHYSICOCHEMICAL PROPERTIES:
CC       pH dependence:
CC         Highly stable from pH 0 to pH 12. {ECO:0000269|PubMed:27853299};
CC       Temperature dependence:
CC         Hyperthermostable. {ECO:0000269|PubMed:27853299};
CC   -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:27853299}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:27853299}.
CC   -!- SIMILARITY: Belongs to the 7 kDa DNA-binding/endoribonuclease P2
CC       family. {ECO:0000305}.
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DR   EMBL; CP000682; ABP94754.1; -; Genomic_DNA.
DR   RefSeq; WP_009071314.1; NC_009440.1.
DR   AlphaFoldDB; A4YEA2; -.
DR   SMR; A4YEA2; -.
DR   STRING; 399549.Msed_0579; -.
DR   EnsemblBacteria; ABP94754; ABP94754; Msed_0579.
DR   GeneID; 5103739; -.
DR   GeneID; 59455970; -.
DR   KEGG; mse:Msed_0579; -.
DR   eggNOG; arCOG05888; Archaea.
DR   HOGENOM; CLU_2929990_0_0_2; -.
DR   OMA; MATKIKF; -.
DR   Proteomes; UP000000242; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:InterPro.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR003212; DNA-bd_7kDa_arc.
DR   Pfam; PF02294; 7kD_DNA_binding; 1.
DR   SUPFAM; SSF54160; SSF54160; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; DNA-binding; Reference proteome.
FT   CHAIN           1..62
FT                   /note="DNA-binding protein 7"
FT                   /id="PRO_0000439049"
SQ   SEQUENCE   62 AA;  6979 MW;  2BACB8289A854F10 CRC64;
     MATKIKFKYK GQDLEVDISK VKKVWKVGKM VSFTYDDNGK TGRGAVSEKD APKELLNMIG
     KK