位置:首页 > 蛋白库 > DNAA1_CHLPN
DNAA1_CHLPN
ID   DNAA1_CHLPN             Reviewed;         460 AA.
AC   Q9Z8M9; Q9JSG4;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Chromosomal replication initiator protein DnaA 1;
GN   Name=dnaA1; Synonyms=dnaA; OrderedLocusNames=CPn_0309, CP_0449, CpB0317;
OS   Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=83558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CWL029;
RX   PubMed=10192388; DOI=10.1038/7716;
RA   Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA   Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT   "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL   Nat. Genet. 21:385-389(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AR39;
RX   PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA   Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA   Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA   Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA   Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA   Salzberg S.L., Eisen J.A., Fraser C.M.;
RT   "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT   AR39.";
RL   Nucleic Acids Res. 28:1397-1406(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J138;
RX   PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA   Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA   Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT   "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT   Japan and CWL029 from USA.";
RL   Nucleic Acids Res. 28:2311-2314(2000).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TW-183;
RA   Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA   Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT   "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT   other Chlamydia strains based on whole genome sequence analysis.";
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation of
CC       chromosomal replication. Binds to the origin of replication; it binds
CC       specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-
CC       TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE001363; AAD18458.1; -; Genomic_DNA.
DR   EMBL; AE002161; AAF38287.1; -; Genomic_DNA.
DR   EMBL; BA000008; BAA98519.1; -; Genomic_DNA.
DR   EMBL; AE009440; AAP98251.1; -; Genomic_DNA.
DR   PIR; E86529; E86529.
DR   PIR; F72092; F72092.
DR   RefSeq; NP_224514.1; NC_000922.1.
DR   RefSeq; WP_010882957.1; NZ_LN847257.1.
DR   AlphaFoldDB; Q9Z8M9; -.
DR   SMR; Q9Z8M9; -.
DR   STRING; 115711.CP_0449; -.
DR   EnsemblBacteria; AAD18458; AAD18458; CPn_0309.
DR   EnsemblBacteria; AAF38287; AAF38287; CP_0449.
DR   GeneID; 45050358; -.
DR   KEGG; cpa:CP_0449; -.
DR   KEGG; cpj:dnaA_1; -.
DR   KEGG; cpn:CPn_0309; -.
DR   KEGG; cpt:CpB0317; -.
DR   PATRIC; fig|115713.3.peg.343; -.
DR   eggNOG; COG0593; Bacteria.
DR   HOGENOM; CLU_026910_3_2_0; -.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000000583; Chromosome.
DR   Proteomes; UP000000801; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA replication; DNA-binding; Nucleotide-binding.
FT   CHAIN           1..460
FT                   /note="Chromosomal replication initiator protein DnaA 1"
FT                   /id="PRO_0000114159"
FT   BINDING         148..155
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   460 AA;  52941 MW;  173379ADBA8E2DA9 CRC64;
     MRAWEEFLLL QEKEIGTNTV DKWLRSLKVL CFDACNLYLE AQDSFQITWF EEHIRHKVKS
     GLVNNNNKPI RVHVTSVDKA APFYKEKQMQ QEKTAYFTMH YGSVNPEMTF SNFLVTPEND
     LPFRVLQEFT KSPDENGGVT FNPIYLFGPE GSGKTHLMQS AISVLRESGG KILYVSSDLF
     TEHLVSAIRS GEMQKFRSFY RNIDALFIED IEVFSGKSAT QEEFFHTFNS LHSEGKLIVV
     SSSYAPVDLV AVEDRLISRF EWGVAIPIHP LVQEGLRSFL MRQVERLSIR IQETALDFLI
     YALSSNVKTL LHALNLLAKR VMYKKLSHQL LYEDDVKTLL KDVLEAAGSV RLTPLKIIRN
     VAQYYGVSQE SILGRSQSRE YVLPRQVAMY FCRQKLSLSY VRIGDVFSRD HSTVISSIRL
     IEQKIEENSH DIHMAIQDIS KNLNSLHKSL EFFPSEEMII
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024