ID   DNAA_AYWBP              Reviewed;         504 AA.
AC   Q2NKC5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000255|HAMAP-Rule:MF_00377};
GN   Name=dnaA {ECO:0000255|HAMAP-Rule:MF_00377}; OrderedLocusNames=AYWB_001;
OS   Aster yellows witches'-broom phytoplasma (strain AYWB).
OC   Bacteria; Tenericutes; Mollicutes; Acholeplasmatales; Acholeplasmataceae;
OC   Candidatus Phytoplasma; Candidatus Phytoplasma asteris.
OX   NCBI_TaxID=322098;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AYWB;
RX   PubMed=16672622; DOI=10.1128/jb.188.10.3682-3696.2006;
RA   Bai X., Zhang J., Ewing A., Miller S.A., Jancso Radek A., Shevchenko D.V.,
RA   Tsukerman K., Walunas T., Lapidus A., Campbell J.W., Hogenhout S.A.;
RT   "Living with genome instability: the adaptation of phytoplasmas to diverse
RT   environments of their insect and plant hosts.";
RL   J. Bacteriol. 188:3682-3696(2006).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation of
CC       chromosomal replication. Binds to the origin of replication; it binds
CC       specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-
CC       TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
CC       {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00377}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00377}.
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DR   EMBL; CP000061; ABC65118.1; -; Genomic_DNA.
DR   RefSeq; WP_011412285.1; NC_007716.1.
DR   AlphaFoldDB; Q2NKC5; -.
DR   SMR; Q2NKC5; -.
DR   STRING; 322098.AYWB_001; -.
DR   EnsemblBacteria; ABC65118; ABC65118; AYWB_001.
DR   KEGG; ayw:AYWB_001; -.
DR   eggNOG; COG0593; Bacteria.
DR   HOGENOM; CLU_026910_3_2_14; -.
DR   OMA; FPAFKIV; -.
DR   OrthoDB; 219876at2; -.
DR   PhylomeDB; Q2NKC5; -.
DR   Proteomes; UP000001934; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA replication; DNA-binding; Nucleotide-binding.
FT   CHAIN           1..504
FT                   /note="Chromosomal replication initiator protein DnaA"
FT                   /id="PRO_1000048604"
FT   BINDING         201..208
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00377"
SQ   SEQUENCE   504 AA;  59585 MW;  6D632B1522FC5D13 CRC64;
     MNNYIKIWDV ILNELSKIYS DEVFKETFSN IKKIKQIEEK IIISVETEFI KNKIYKMYFE
     KIKEINKLKF EEKIIIEFVS ENNKKNCNFD NEKKHFENIK KELKNETEIF FCKIENNDEF
     KNNKHFRKNE IKQIENGYND NINVEIENRK ISFNKYNYGN TNPKYSFDNF VVGKSNNFAF
     KISKKIAEEK KVTTNPLYIF GKSGIGKTHL IQAIGNHILK NTHSSKKVLY VKADGFIEEF
     TNQLRKAKME DFNEKYRDID LLLVDDIQIM AGATRTQMEF FKLFDYLYLN QKQIVITSDK
     QASELKNIMS RLTSRFEAGL MVDIQSPDFN HRLNILKKKI LEFEPQNTLK IKKDVLDLIA
     SSFVNNVREM EGALLRLLNY AQTFGYDIDI NIANEALELL IKSKKSVSYD EDVLEKIKLV
     VSNFFNISVR DLMSKKRQQK YTFPRHIAIY LIKELKDIPY NIVGSFFKRN HSAVFKAYQK
     IKKNSQSDYE LKKSLELILK KINS