ID   DNAA_ZYMMO              Reviewed;         484 AA.
AC   Q9S493; Q5NMT0; Q9Z5V1;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Chromosomal replication initiator protein DnaA;
GN   Name=dnaA; OrderedLocusNames=ZMO1356;
OS   Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Zymomonadaceae; Zymomonas.
OX   NCBI_TaxID=264203;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 31821 / ZM4 / CP4;
RA   Um H.W., Kang H.S.;
RL   Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31821 / ZM4 / CP4;
RX   PubMed=15592456; DOI=10.1038/nbt1045;
RA   Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H.,
RA   Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J.,
RA   Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y., Kang H.L., Lee S.Y., Lee K.J.,
RA   Kang H.S.;
RT   "The genome sequence of the ethanologenic bacterium Zymomonas mobilis
RT   ZM4.";
RL   Nat. Biotechnol. 23:63-68(2005).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation of
CC       chromosomal replication. Binds to the origin of replication; it binds
CC       specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-
CC       TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000305}.
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DR   EMBL; AF157493; AAD42393.1; -; Genomic_DNA.
DR   EMBL; AF124349; AAD19709.1; -; Genomic_DNA.
DR   EMBL; AE008692; AAV89980.1; -; Genomic_DNA.
DR   RefSeq; WP_011241150.1; NZ_CP035711.1.
DR   AlphaFoldDB; Q9S493; -.
DR   SMR; Q9S493; -.
DR   STRING; 264203.ZMO1356; -.
DR   PRIDE; Q9S493; -.
DR   EnsemblBacteria; AAV89980; AAV89980; ZMO1356.
DR   GeneID; 58027103; -.
DR   KEGG; zmo:ZMO1356; -.
DR   eggNOG; COG0593; Bacteria.
DR   HOGENOM; CLU_026910_3_0_5; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000001173; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA replication; DNA-binding; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..484
FT                   /note="Chromosomal replication initiator protein DnaA"
FT                   /id="PRO_0000114312"
FT   REGION          110..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         188..195
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        390
FT                   /note="R -> P (in Ref. 1; AAD42393)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   484 AA;  55195 MW;  7279609CE89D5B46 CRC64;
     MQPPSQDWAS LLPAAWSEAR QILRKKCGSR TFESWLKSLM LADFDSQKKI IRLACPSEFM
     ANWISSHLSD ELLLAWRTVW PGIAEVKVSV RNPESQPLLL DVTEIELPLG DQPRPLPKKP
     AKKKQSVPAT PKSTSPEKKA EGEDQNQFEE RYNFDNFVVG KANDLAYRAA CTFAEGGKLD
     FNPLFLYGGT GLGKTHLMHA VGIEYLKRHP NSTALYMSAE KFMYDFVASM RAKDTHSFKA
     RLRSADLLMI DDVQFIAGKD STQEEFFHTM NEVITAGRRL VISADRSPQD LERIESRILS
     RLSWGLVADV NPADFELRLN IILKKLEAMP QVSMPEDIVF FLAKRICTNV RELEGALNRV
     VAYATLSNRP INMDFVTETL ADLLRTTQQR VTVEDIQKRV CDHYHLKLAD MSSKRRDRVI
     ARPRQVAMYL SKQLTSRSLP EIGQRFGGRD HTTVIHAIRQ IEKLRITDED VDSDVRLLMR
     QFEG