ID   DNAC_BUCAP              Reviewed;         246 AA.
AC   Q8KA79;
DT   08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=DNA replication protein DnaC;
GN   Name=dnaC; OrderedLocusNames=BUsg_022;
OS   Buchnera aphidicola subsp. Schizaphis graminum (strain Sg).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=198804;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sg;
RX   PubMed=12089438; DOI=10.1126/science.1071278;
RA   Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S.,
RA   Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
RT   "50 million years of genomic stasis in endosymbiotic bacteria.";
RL   Science 296:2376-2379(2002).
CC   -!- FUNCTION: This protein is required for chromosomal replication. It
CC       forms, in concert with DnaB protein and other prepriming proteins DnaT,
CC       N, N', N'' a prepriming protein complex on the specific site of the
CC       template DNA recognized by protein N' (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DnaC family. {ECO:0000305}.
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DR   EMBL; AE013218; AAM67594.1; -; Genomic_DNA.
DR   RefSeq; WP_011053560.1; NC_004061.1.
DR   AlphaFoldDB; Q8KA79; -.
DR   SMR; Q8KA79; -.
DR   STRING; 198804.BUsg_022; -.
DR   EnsemblBacteria; AAM67594; AAM67594; BUsg_022.
DR   KEGG; bas:BUsg_022; -.
DR   eggNOG; COG1484; Bacteria.
DR   HOGENOM; CLU_062999_3_1_6; -.
DR   OMA; VGDLMKR; -.
DR   OrthoDB; 1792718at2; -.
DR   Proteomes; UP000000416; Chromosome.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR028350; DNAC/ATP-binding.
DR   InterPro; IPR002611; IstB_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01695; IstB_IS21; 1.
DR   PIRSF; PIRSF003073; DNAC_TnpB_IstB; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   DNA replication; Primosome.
FT   CHAIN           1..246
FT                   /note="DNA replication protein DnaC"
FT                   /id="PRO_0000079952"
FT   SITE            69
FT                   /note="Probably involved in the interaction with the DnaB
FT                   protein"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   246 AA;  28498 MW;  BF7E2A9BC2ADBB5D CRC64;
     MTFYNEFFKR LQRLMPSNVK PKFESDQDLL AWNQEQGRLS SESILRENKA MKMQRVLGRS
     GIRELYMNCS FENYKIEHDG QRKVLKAAKR YAEEFNENIA SFIFSGRPGT GKNHLASAIG
     NYLILHGKSI LIVTVADLMS NMKGTFSGTS NITEENLLHN LSSVDLLMID EIGMQTESRY
     EKVIINQIVD RRSSSKRSTG MLSNLDHRGM KNLLGERVID RMRLGNSLWL TFEWDSYRQY
     VRGDEY