ID   DNAC_SHIFL              Reviewed;         245 AA.
AC   P0AEF3; P07905;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=DNA replication protein DnaC;
GN   Name=dnaC; OrderedLocusNames=SF4392, S4662;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: This protein is required for chromosomal replication. It
CC       forms, in concert with DnaB protein and other prepriming proteins DnaT,
CC       N, N', N'' a prepriming protein complex on the specific site of the
CC       template DNA recognized by protein N' (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DnaC family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN45807.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP19585.1; -; Genomic_DNA.
DR   RefSeq; NP_710100.1; NC_004337.2.
DR   RefSeq; WP_000799911.1; NZ_WPGW01000045.1.
DR   AlphaFoldDB; P0AEF3; -.
DR   SMR; P0AEF3; -.
DR   STRING; 198214.SF4392; -.
DR   EnsemblBacteria; AAN45807; AAN45807; SF4392.
DR   EnsemblBacteria; AAP19585; AAP19585; S4662.
DR   GeneID; 1026688; -.
DR   GeneID; 66671753; -.
DR   KEGG; sfl:SF4392; -.
DR   KEGG; sfx:S4662; -.
DR   PATRIC; fig|198214.7.peg.5178; -.
DR   HOGENOM; CLU_062999_3_1_6; -.
DR   OMA; VGDLMKR; -.
DR   OrthoDB; 1792718at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR028350; DNAC/ATP-binding.
DR   InterPro; IPR002611; IstB_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01695; IstB_IS21; 1.
DR   PIRSF; PIRSF003073; DNAC_TnpB_IstB; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA replication; Nucleotide-binding; Primosome;
KW   Reference proteome.
FT   CHAIN           1..245
FT                   /note="DNA replication protein DnaC"
FT                   /id="PRO_0000079957"
FT   SITE            69
FT                   /note="Probably involved in the interaction with the DnaB
FT                   protein"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   245 AA;  27935 MW;  C5CC7232E21F11F1 CRC64;
     MKNVGDLMQR LQKMMPAHIK PAFKTGEELL AWQKEQGAIR SAALERENRA MKMQRTFNRS
     GIRPLHQNCS FENYRVECEG QMNALSKARQ YVEEFDGNIA SFIFSGKPGT GKNHLAAAIC
     NELLLRGKSV LIITVADIMS AMKDTFRNSG TSEEQLLNDL SNVDLLVIDE IGVQTESKYE
     KVIINQIVDR RSSSKRPTGM LTNSNMEEMT KLLGERVMDR MRLGNSLWVI FNWDSYRSRV
     TGKEY