DNAD_BACSU
ID DNAD_BACSU Reviewed; 232 AA.
AC P39787;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=DNA replication protein DnaD;
GN Name=dnaD; OrderedLocusNames=BSU22350;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=7704260; DOI=10.1099/13500872-141-2-321;
RA Bruand C., Sorokin A., Serror P., Ehrlich S.D.;
RT "Nucleotide sequence of the Bacillus subtilis dnaD gene.";
RL Microbiology 141:321-322(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC 3610 / NRRL NRS-744 / VKM B-501;
RX PubMed=8760912; DOI=10.1099/13500872-142-8-2005;
RA Sorokin A.V., Azevedo V., Zumstein E., Galleron N., Ehrlich S.D.,
RA Serror P.;
RT "Sequence analysis of the Bacillus subtilis chromosome region between the
RT serA and kdg loci cloned in a yeast artificial chromosome.";
RL Microbiology 142:2005-2016(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- FUNCTION: Probable component of primosome involved in the initiation of
CC DNA replication.
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DR EMBL; U11289; AAA80004.1; -; Genomic_DNA.
DR EMBL; L47709; AAB38456.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB14151.1; -; Genomic_DNA.
DR PIR; I40524; I40524.
DR RefSeq; NP_390116.1; NC_000964.3.
DR RefSeq; WP_004398499.1; NZ_JNCM01000036.1.
DR PDB; 2V79; X-ray; 2.00 A; A/B=1-127.
DR PDBsum; 2V79; -.
DR AlphaFoldDB; P39787; -.
DR SMR; P39787; -.
DR IntAct; P39787; 1.
DR STRING; 224308.BSU22350; -.
DR PaxDb; P39787; -.
DR PRIDE; P39787; -.
DR EnsemblBacteria; CAB14151; CAB14151; BSU_22350.
DR GeneID; 939040; -.
DR KEGG; bsu:BSU22350; -.
DR eggNOG; COG3935; Bacteria.
DR OMA; FHYKDIF; -.
DR PhylomeDB; P39787; -.
DR BioCyc; BSUB:BSU22350-MON; -.
DR EvolutionaryTrace; P39787; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 1.
DR Gene3D; 1.10.10.630; -; 1.
DR InterPro; IPR034829; DnaD-like_sf.
DR InterPro; IPR006343; DnaD_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR Pfam; PF07261; DnaB_2; 1.
DR SUPFAM; SSF158499; SSF158499; 1.
DR TIGRFAMs; TIGR01446; DnaD_dom; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA replication; Primosome; Reference proteome.
FT CHAIN 1..232
FT /note="DNA replication protein DnaD"
FT /id="PRO_0000079958"
FT MUTAGEN 166
FT /note="A->T: In dnaD23; temperature-sensitive mutant that
FT affects the initiation of chromosome replication."
FT HELIX 3..12
FT /evidence="ECO:0007829|PDB:2V79"
FT STRAND 14..18
FT /evidence="ECO:0007829|PDB:2V79"
FT HELIX 19..28
FT /evidence="ECO:0007829|PDB:2V79"
FT HELIX 32..45
FT /evidence="ECO:0007829|PDB:2V79"
FT TURN 46..48
FT /evidence="ECO:0007829|PDB:2V79"
FT HELIX 54..58
FT /evidence="ECO:0007829|PDB:2V79"
FT STRAND 61..63
FT /evidence="ECO:0007829|PDB:2V79"
FT HELIX 65..78
FT /evidence="ECO:0007829|PDB:2V79"
FT STRAND 82..87
FT /evidence="ECO:0007829|PDB:2V79"
FT STRAND 93..98
FT /evidence="ECO:0007829|PDB:2V79"
FT HELIX 100..114
FT /evidence="ECO:0007829|PDB:2V79"
SQ SEQUENCE 232 AA; 27639 MW; 0C525940F7F77E30 CRC64;
MKKQQFIDMQ EQGTSTIPNL LLTHYKQLGL NETELILLLK IKMHLEKGSY FPTPNQLQEG
MSISVEECTN RLRMFIQKGF LFIEECEDQN GIKFEKYSLQ PLWGKLYEYI QLAQNQTQER
KAEGEQKSLY TIFEEEFARP LSPLECETLA IWQDQDQHDA QLIKHALKEA VLSGKLSFRY
IDRILFEWKK NGLKTVEQAK IHSQKFRRVQ AKQNEPQKEY KRQVPFYNWL EQ
