ID   DNAE2_XANOR             Reviewed;        1083 AA.
AC   Q5GX78;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Error-prone DNA polymerase {ECO:0000255|HAMAP-Rule:MF_01902};
DE            EC=2.7.7.7 {ECO:0000255|HAMAP-Rule:MF_01902};
GN   Name=dnaE2 {ECO:0000255|HAMAP-Rule:MF_01902}; OrderedLocusNames=XOO3439;
OS   Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xanthomonas.
OX   NCBI_TaxID=291331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KACC10331 / KXO85;
RX   PubMed=15673718; DOI=10.1093/nar/gki206;
RA   Lee B.-M., Park Y.-J., Park D.-S., Kang H.-W., Kim J.-G., Song E.-S.,
RA   Park I.-C., Yoon U.-H., Hahn J.-H., Koo B.-S., Lee G.-B., Kim H.,
RA   Park H.-S., Yoon K.-O., Kim J.-H., Jung C.-H., Koh N.-H., Seo J.-S.,
RA   Go S.-J.;
RT   "The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the
RT   bacterial blight pathogen of rice.";
RL   Nucleic Acids Res. 33:577-586(2005).
CC   -!- FUNCTION: DNA polymerase involved in damage-induced mutagenesis and
CC       translesion synthesis (TLS). It is not the major replicative DNA
CC       polymerase. {ECO:0000255|HAMAP-Rule:MF_01902}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01902};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01902}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-C family. DnaE2
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01902}.
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DR   EMBL; AE013598; AAW76693.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q5GX78; -.
DR   SMR; Q5GX78; -.
DR   STRING; 291331.XOO3439; -.
DR   EnsemblBacteria; AAW76693; AAW76693; XOO3439.
DR   KEGG; xoo:XOO3439; -.
DR   PATRIC; fig|291331.8.peg.3800; -.
DR   HOGENOM; CLU_001600_4_0_6; -.
DR   OMA; NSWPMGF; -.
DR   Proteomes; UP000006735; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   HAMAP; MF_01902; DNApol_error_prone; 1.
DR   InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR   InterPro; IPR040982; DNA_pol3_finger.
DR   InterPro; IPR023073; DNA_pol_error_prone.
DR   InterPro; IPR029460; DNAPol_HHH.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   InterPro; IPR004805; PolC_alpha.
DR   PANTHER; PTHR32294; PTHR32294; 1.
DR   PANTHER; PTHR32294:SF4; PTHR32294:SF4; 1.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF17657; DNA_pol3_finger; 1.
DR   Pfam; PF14579; HHH_6; 1.
DR   Pfam; PF02811; PHP; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF89550; SSF89550; 1.
DR   TIGRFAMs; TIGR00594; polc; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-directed DNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transferase.
FT   CHAIN           1..1083
FT                   /note="Error-prone DNA polymerase"
FT                   /id="PRO_0000103407"
SQ   SEQUENCE   1083 AA;  120455 MW;  2F19994AA0FB2727 CRC64;
     MSWDDAIEGV DRDTPGGRMP RAWNVAARLR AANDDISHAH VADGVPTYAE LHCLSDFSFL
     RGASSAEQLF ARAQHCGYSA LAITDECSLA GIVRGLEASR VTGVRLIVGS EFTLIDGTRF
     VLLVENAHGY PQVCGLVTTA RRAASKGAYR LGRADVEAQF RDVAPGVFAL WLPGVQPQAE
     QGAWLQQVFG ERAFLAVELH REQDDGARLQ VLQALAQQLG MTAVASGDVH MAQRRERIVQ
     DTLTAIRHTL PLAECGAHLF RNGERHLRTR RALGNIYPDA LLQAAVALAQ RCTFDISKIS
     YTYPRELVPE GHTPTSYLRQ LTEAGIRKRW PGGITAKVRE DIEKELALIA LKKYEAFFLT
     VQDVVRFARE QNILCQGRGS SANSAVCYAL GITAVNPDET RLLMARFLSE KRDEPPDIDV
     DFEHERREEV LQYVYRKYGR ERAALAATVI CYRGKSAVRD VAKAFGLPPD QIALLANCYG
     WGNGETPMEQ RIEEAGFDLA NPLINKILLV TEHLRDHPRH LSQHVGGFVI SDEPLSLLVP
     VENAAMADRT IIQWDKDDLE TMKLLKVDCL ALGMLTCIRK TLDLVRGHRG RDYSIATLPG
     EDLPTYKMIQ RADTVGVFQI ESRAQMAMLP RLKPAEFYDL VIEVAIVRPG PIQGDMVHPY
     LRRRQGREDV SYPSPAVEDI LKPTLGVPLF QEQVMELLMH AADYTESEAD NLRRSMAAWR
     RGGDMEQHRM RVRERMQGKG YASTFIDQIF EQIKGFGSYG FPQSHAASFA KLVYASCWLK
     RHEPAAFACG LLNAQPMGFY SASQIVQDAR RGSPERERVE VLPVDVVHSD WDNTLVGGRP
     WRSAADPGEQ PAIRLGMRQV AGLSDVVAQR IVAARTQRAF ADIGDLCLRA ALDEKACLAL
     AEAGALQGMV GNRNAARWAM AGVEARRPLL PGSPEERPVA FEAPHAGEEI LADYRSVGLS
     LRQHPMALLR PQMRQRRILG LRDLQGRPHG SGVHVAGLVT QRQRPATAKG TIFVTLEDEH
     GMINVIVWSH LALRRRRALL ESRLLAVRGR WERVDGVEHL IAGDLHDLSD LLGDMQLPSR
     DFH