ID   DNAK1_NOSS1             Reviewed;         688 AA.
AC   Q9ZEJ6;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 2.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Chaperone protein dnaK1;
DE   AltName: Full=HSP70-1;
DE   AltName: Full=Heat shock 70 kDa protein 1;
DE   AltName: Full=Heat shock protein 70-1;
GN   Name=dnaK1; Synonyms=dnaK; OrderedLocusNames=alr2990;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Pohl B.;
RL   Thesis (1999), University of Bonn, Germany.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; AJ132707; CAA10744.1; -; Genomic_DNA.
DR   EMBL; BA000019; BAB74689.1; -; Genomic_DNA.
DR   PIR; AG2179; AG2179.
DR   RefSeq; WP_010997141.1; NZ_RSCN01000003.1.
DR   AlphaFoldDB; Q9ZEJ6; -.
DR   SMR; Q9ZEJ6; -.
DR   STRING; 103690.17132084; -.
DR   EnsemblBacteria; BAB74689; BAB74689; BAB74689.
DR   KEGG; ana:alr2990; -.
DR   eggNOG; COG0443; Bacteria.
DR   OMA; PCQSVNP; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..688
FT                   /note="Chaperone protein dnaK1"
FT                   /id="PRO_0000078407"
FT   REGION          630..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        630..667
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        258..261
FT                   /note="MEAA -> HGRRR (in Ref. 1; CAA10744)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        304
FT                   /note="C -> Q (in Ref. 1; CAA10744)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        361
FT                   /note="N -> D (in Ref. 1; CAA10744)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        376
FT                   /note="I -> N (in Ref. 1; CAA10744)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        508
FT                   /note="N -> D (in Ref. 1; CAA10744)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   688 AA;  76777 MW;  C0816632DDB2E5B1 CRC64;
     MGKVVGIDLG TTNSVVAVME GGKPVVIANA EGMRTTPSVV GFSKDGERVV GQMARRQTVL
     NPQNTFFAVK RYIGRRYNEL SPESKRVPYT IRKDEVGNIK VACPRLNKEF SAEEISAMVL
     KKLADDASAY LGSAVTGAVI TVPAYFNDSQ RQATRDAGRI AGLEVLRILN EPTAASLAYG
     LDRGDTETIL VFDLGGGTFD VSILEVGDGV FEVKATSGDT QLGGNDFDKK IVDWLAEQFL
     ETEGVDLRRD RQALQRLMEA AEKAKIELSA VSITDINLPF ITATEDGPKH LETRLTRSQF
     EGLCVDLLGR VRNPVKRALK DAGLRPDDIE EVVLVGGSTR MPMVKQLVRD LIGIEPSENV
     NPDEVVAMGA AIQAGILAGE FKDVLLLDVT PLSLGLEAIG GVMKKLIPRN TTIPVRRSDI
     FSTSENNQNS VEIHVVQGER EMAGDNKSLG RFKLYGIPPA PRGIPQIQVA FDIDANGILQ
     VTALDRTTGR EQSITIQGAS TLSESEVNRM IQEAQKYADV DRERKERVEK RTRSEALILQ
     GERQLREVAL EFGMQFARNR RQRIDNISRE LKESLKENDD RGIDQAYADL QDALYELNRE
     VRQYYAEDED DDLFATIKDI FVGDKDKERD LPRDSYRERD AYNNRDYGRD YGRDYGRDSR
     PSYDNSRPPR KSPRPSYQDN WDDDDDWL