ID   DNAK1_PHOPR             Reviewed;         639 AA.
AC   Q6LUA7;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Chaperone protein DnaK 1 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 1 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein 1 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 1 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK1 {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=PBPRA0697;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR378665; CAG19118.1; -; Genomic_DNA.
DR   RefSeq; WP_011217464.1; NC_006370.1.
DR   AlphaFoldDB; Q6LUA7; -.
DR   SMR; Q6LUA7; -.
DR   STRING; 298386.PBPRA0697; -.
DR   PRIDE; Q6LUA7; -.
DR   EnsemblBacteria; CAG19118; CAG19118; PBPRA0697.
DR   KEGG; ppr:PBPRA0697; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_6; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000000593; Chromosome 1.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..639
FT                   /note="Chaperone protein DnaK 1"
FT                   /id="PRO_0000225992"
FT   REGION          603..639
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        617..639
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         199
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   639 AA;  69359 MW;  AB5AE4D04A7600DC CRC64;
     MGRIIGIDLG TTNSCVAVLD GDKPRVIENA EGERTTASVV AYTQDGETLV GQPAKRQAVT
     NPENTLYAIK RLIGRRFEDE EVQRDLKIMP FKIVKADNGD AWVEAKGQKM AAPQVSAEIL
     KKMKKTAEDF LGEEVTAAVI TVPAYFNDAQ RQATKDAGRI AGLEVKRIIN EPTAAALAYG
     LDKKGGDRTI AVYDLGGGTF DISIIEIDEV EGEKTFEVLS TNGDTHLGGE DFDNRLINYL
     VEEFKKEQGM DLRNDPLAMQ RLKEAAEKAK IELSSAQQTD VNLPYITADA TGPKHMNIKV
     TRAKLESLVE DLVQRSLEPL KVALSDAGLS VSEITDIIVV GGQTRMPMVQ AKVAEFFGKE
     PRKDVNPDEA VAVGAAVQAG VLAGDVKDVL LLDVTPLSLG IETMGGVMTK LIEKNTTIPT
     KANQVFSTAE DNQSAVTIHV LQGERKQSSY NKSLGQFNLE GIQAAARGMP QIEVTFDLDA
     DGILHVSAKD KSTGKEQKIT IQSSSGLSEE DIEKMVQEAE ANKESDKKFE ELVTARNQAD
     QLIHGTRKQV EEAGEALPAE DKEKIEAAVS ELEEARKAED KEAIDAKVQA LVAASQKLME
     IAQQQAQAQQ APGGEGEQEA KQDDNVVDAE FEEVKDEKK