ID   DNAK1_SYNP6             Reviewed;         749 AA.
AC   Q5N1V0;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Chaperone protein DnaK 1 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 1 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein 1 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 1 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK1 {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=syc1530_d;
OS   Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS   nidulans).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=269084;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX   PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA   Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA   Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT   "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT   Synechococcus elongatus PCC 6301 chromosome: gene content and
RT   organization.";
RL   Photosyn. Res. 93:55-67(2007).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; AP008231; BAD79720.1; -; Genomic_DNA.
DR   RefSeq; WP_011243840.1; NC_006576.1.
DR   AlphaFoldDB; Q5N1V0; -.
DR   SMR; Q5N1V0; -.
DR   STRING; 269084.syc1530_d; -.
DR   EnsemblBacteria; BAD79720; BAD79720; syc1530_d.
DR   KEGG; syc:syc1530_d; -.
DR   eggNOG; COG0443; Bacteria.
DR   OMA; PCQSVNP; -.
DR   Proteomes; UP000001175; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..749
FT                   /note="Chaperone protein DnaK 1"
FT                   /id="PRO_0000226021"
FT   REGION          643..749
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        643..694
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        707..723
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   749 AA;  84194 MW;  DE83C1EC2B6E94C3 CRC64;
     MGRVVGIDLG TTNSVIAVME GGKPMVIANA EGVRTTPSVV GVSKTGERLV GELARRQLVL
     NPRNTFANIK RFIGRRYDEL TDESKRVPYT VRRDPEGNVR IVCPQLSREF APEEVAAMIL
     RKLAEEASRY LGEPVTGAVI TVPAYFNDSQ RQATRDAGRI AGLEVKRILN EPTAASLAYG
     LDRRDNQTIL VFDLGGGTFD VSVLEVGNGV FEVKATSGDT QLGGNDFDRR IVDWLAEQFL
     EAEGIDLRRD RQALQRLIEA AEKAKIELSG VSVTDINLPF ITATEDEPKH LETRLTRSEF
     EALCEDLLER MMRPLRRALK DARLQPQDID EVVLVGGSTR MPMVQQLVRS LIGREPNQNV
     NPDEVVAIGA AIQAGILAGE VKDILLLDVT PLSLGLETIG GVMKKLIPRN TAIPVRRSDI
     FSTAENNQTM VEIHILQGER QLAEGNKSLG RFKLTGIPPA PRGVPQVQVS FDIDANGILQ
     VSALDKTTGR EQTVTIQGAS TLSQEEVKRM MKDAELYAQQ DRQLKARIEK RNRAQTLIAQ
     SERRLREISL DFGLYFAESK RRRIESTIRE LKDYLERQDD RGLDLALAEL QDALFDLNQE
     TAARLRDEEG EGFFEPLKQT FASLRGDGNR DFERSWDDRG GDRWDADPWD RSRRSTPSYG
     YDDRRSPVSD PYRGERWVEE QTSMSRREPV RDRNGGNGSV RPEPAPRRGR PTWEEDQPPR
     RDRSSQPPAK PASGRRWNDG WDDDDDEWF