ID   DNAK2_COLP3             Reviewed;         638 AA.
AC   Q47XI6;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Chaperone protein DnaK 2 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 2 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein 2 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 2 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK2 {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=CPS_3821;
OS   Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio
OS   psychroerythus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Colwelliaceae; Colwellia.
OX   NCBI_TaxID=167879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=34H / ATCC BAA-681;
RX   PubMed=16043709; DOI=10.1073/pnas.0504766102;
RA   Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X.,
RA   Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M.,
RA   Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A.,
RA   Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B.,
RA   Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
RT   "The psychrophilic lifestyle as revealed by the genome sequence of
RT   Colwellia psychrerythraea 34H through genomic and proteomic analyses.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP000083; AAZ27124.1; -; Genomic_DNA.
DR   RefSeq; WP_011044570.1; NC_003910.7.
DR   AlphaFoldDB; Q47XI6; -.
DR   SMR; Q47XI6; -.
DR   STRING; 167879.CPS_3821; -.
DR   EnsemblBacteria; AAZ27124; AAZ27124; CPS_3821.
DR   KEGG; cps:CPS_3821; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_6; -.
DR   OMA; DKMVLQR; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000000547; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..638
FT                   /note="Chaperone protein DnaK 2"
FT                   /id="PRO_0000225952"
FT   REGION          604..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         199
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   638 AA;  68766 MW;  FA89096B20160DBA CRC64;
     MGKIIGIDLG TTNSCVAVLD GDSVRVIENA EGDRTTPSII GYTAEGETLV GQPAKRQSVT
     NPENTLYAIK RLIGRRFEDK ETQRDIDIMP FGIVKADNGD AWVQVKGEKI APPQVSAEVL
     KKMKKTAEDF LGETVTEAVI TVPAYFNDSQ RQATKDAGRI AGLEVKRIIN EPTAAALAYG
     MDKQEGDKVV AVYDLGGGTF DISIIEIDEM DGEHTFEVLA TNGDTHLGGE DFDNRLINYL
     VAEFKKDQGM DLTSDPLAMQ RLKEAAEKAK CELSSAQQTD VNLPYITADG SGPKHMNIKV
     TRAKLESLVE DMVKATLEPL KQALKDADLS VSKIDDVILV GGQSRMPLVQ KTVTDFFGKE
     PRKDVNPDEA VASGAAIQAG VLSGDVTDVL LLDVTPLSLG IETMGGVMTK VIDKNTTIPT
     KQSQTFSTAD DNQAAVTVHV CQGERKQASA NKSLGQFNLE GIEPAQRGTP QIEVTFDIDA
     DGILHVTAKD KNTGKEQKIT IKASSGLSDE EVEQMVRDAE ANADADAKFE ELVTARNQAD
     GMIHATRKQV EEAGEELPSE DKEKIEAALT ELEEAVKGDD KEVIEAKTQA LMEASAKLME
     IAQAKEQAQS APEGAQEADA APADDVVDAE FEEVKDDK