ID   DNAK2_SYNP6             Reviewed;         634 AA.
AC   Q5N1J4;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Chaperone protein DnaK 2 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 2 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein 2 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 2 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK2 {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=syc1636_c;
OS   Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) (Anacystis
OS   nidulans).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=269084;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27144 / PCC 6301 / SAUG 1402/1;
RX   PubMed=17211581; DOI=10.1007/s11120-006-9122-4;
RA   Sugita C., Ogata K., Shikata M., Jikuya H., Takano J., Furumichi M.,
RA   Kanehisa M., Omata T., Sugiura M., Sugita M.;
RT   "Complete nucleotide sequence of the freshwater unicellular cyanobacterium
RT   Synechococcus elongatus PCC 6301 chromosome: gene content and
RT   organization.";
RL   Photosyn. Res. 93:55-67(2007).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; AP008231; BAD79826.1; -; Genomic_DNA.
DR   RefSeq; WP_011243946.1; NC_006576.1.
DR   AlphaFoldDB; Q5N1J4; -.
DR   SMR; Q5N1J4; -.
DR   STRING; 269084.syc1636_c; -.
DR   EnsemblBacteria; BAD79826; BAD79826; syc1636_c.
DR   KEGG; syc:syc1636_c; -.
DR   eggNOG; COG0443; Bacteria.
DR   OMA; AYTKNQD; -.
DR   Proteomes; UP000001175; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..634
FT                   /note="Chaperone protein DnaK 2"
FT                   /id="PRO_0000226019"
FT   REGION          600..634
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        600..624
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         197
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   634 AA;  67776 MW;  FD2F1A68901E03B7 CRC64;
     MAKVVGIDLG TTNSCVAVME GGKPTVIANA EGFRTTPSVV AFAKNQDRLV GQIAKRQAVM
     NPENTFYSVK RFIGRRPDEV TNELTEVAYK VDTSGNAVKL DSSNAGKQFA PEEISAQVLR
     KLAEDASKYL GETVTQAVIP VPAYFNDSQR QATKDAGKIA GLEVLRIINE PTAAALAYGL
     DKKSNERILV FDLGGGTFDV SVLEVGDGVF EVLATSGDTH LGGDDFDKKI VDFLAGEFQK
     NEGIDLRKDK QALQRLTEAA EKAKIELSSA TQTEINLPFI TATQDGPKHL DLTLTRAKFE
     ELASDLIDRC RIPVEQAIKD AKLALSEIDE IVLVGGSTRI PAVQAIVKQM TGKEPNQSVN
     PDEVVAIGAA IQGGVLAGEV KDILLLDVTP LSLGVETLGG VMTKLIPRNT TIPTKKSETF
     STAADGQTNV EIHVLQGERE MASDNKSLGT FRLDGIPPAP RGVPQIEVIF VIDANGILNV
     TAKDKGSGKE QSISITGAST LSDNEVDRMV KDAEANAAAD KERRERIDLK NQADTLVYQS
     EKQLSELGDK ISADEKSKVE GFIQELKDAL AAEDYDKIRS IIEQLQQALY AAGSSVYQQA
     SAEASANAQA GPSSSSSSSS GDDDVIDAEF SESK