ID   DNAK2_THEVB             Reviewed;         640 AA.
AC   Q8DI58;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Chaperone protein dnaK2;
DE   AltName: Full=HSP70-2;
DE   AltName: Full=Heat shock 70 kDa protein 2;
DE   AltName: Full=Heat shock protein 70-2;
GN   Name=dnaK2; OrderedLocusNames=tlr1733;
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000039; BAC09285.1; -; Genomic_DNA.
DR   RefSeq; NP_682523.1; NC_004113.1.
DR   RefSeq; WP_011057570.1; NC_004113.1.
DR   AlphaFoldDB; Q8DI58; -.
DR   SMR; Q8DI58; -.
DR   STRING; 197221.22295459; -.
DR   PRIDE; Q8DI58; -.
DR   EnsemblBacteria; BAC09285; BAC09285; BAC09285.
DR   KEGG; tel:tlr1733; -.
DR   PATRIC; fig|197221.4.peg.1814; -.
DR   eggNOG; COG0443; Bacteria.
DR   OMA; AYTKNQD; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..640
FT                   /note="Chaperone protein dnaK2"
FT                   /id="PRO_0000078561"
FT   REGION          605..640
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        605..625
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         197
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   640 AA;  68927 MW;  9109BC3523AABEAC CRC64;
     MAKVVGIDLG TTNSCVAVME GGKPTVIANA EGFRTTPSVV AYTKNGDRLV GQIAKRQAVM
     NPENTFYSVK RFIGRRFDEV THEATEVSYK VLNVNGNVKL DCPALGKQFA PEEISAQVLR
     KLKEDASKYL GEEVTQAVIT VPAYFNDSQR QATKDAGKIA GLEVLRIINE PTAASLAYGL
     DKKANETILV FDLGGGTFDV SILEVGDGVF EVLATSGDTH LGGDDFDKKI VDYLAESFRA
     QEGIDLRKDR QALQRLTEAA EKAKIELSSV MQTEINLPFI TATQDGPKHL DMTLTRAKFE
     ELCSDLIDRC RVPVEQALKD AKLSKDQIDE VVLVGGSTRI PAIQELVKRL LGKDPNQSVN
     PDEVVAVGAA IQAGVLAGEV KDILLLDVTP LSLGVETLGG VMTKIIPRNT TIPTKKSEVF
     STAVDGQTNV EIHVLQGERE MAADNKSLGT FRLDGIPPAP RGVPQIEVTF DIDANGILNV
     TARDKGTGKQ QSISITGAST LPKEEVERMV REAEMNAAAD KAKREKIETK NQAEQLCYQA
     EKQLNELGDK VSTSDKDRLT SLIANLRSEI GTEAEKKPID AIDFGRVKSL MQDLQQALYS
     VGSSVYQSAQ SSDGTGSSSS GGSGSGGDDE VIDAEFSETK