ID   DNAK3_SYNE7             Reviewed;         749 AA.
AC   P50022; Q31K09;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Chaperone protein dnaK3;
DE   AltName: Full=HSP70-3;
DE   AltName: Full=Heat shock 70 kDa protein 3;
DE   AltName: Full=Heat shock protein 70-3;
GN   Name=dnaK3; OrderedLocusNames=Synpcc7942_2580;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8003021; DOI=10.1006/bbrc.1994.1778;
RA   Nimura K., Yoshikawa H., Takahashi H.;
RT   "Sequence analysis of the third dnaK homolog gene in Synechococcus sp.
RT   PCC7942.";
RL   Biochem. Biophys. Res. Commun. 201:848-854(1994).
RN   [2]
RP   ERRATUM OF PUBMED:8003021.
RX   PubMed=7811295; DOI=10.1006/bbrc.1994.2908;
RA   Nimura K., Yoshikawa H., Takahashi H.;
RL   Biochem. Biophys. Res. Commun. 205:2016-2017(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; D29968; BAA06234.1; -; Genomic_DNA.
DR   EMBL; CP000100; ABB58610.1; -; Genomic_DNA.
DR   PIR; JC2458; JC2458.
DR   RefSeq; WP_011378523.1; NC_007604.1.
DR   AlphaFoldDB; P50022; -.
DR   SMR; P50022; -.
DR   STRING; 1140.Synpcc7942_2580; -.
DR   PRIDE; P50022; -.
DR   EnsemblBacteria; ABB58610; ABB58610; Synpcc7942_2580.
DR   KEGG; syf:Synpcc7942_2580; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_3; -.
DR   OMA; PCQSVNP; -.
DR   OrthoDB; 161217at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_2580-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..749
FT                   /note="Chaperone protein dnaK3"
FT                   /id="PRO_0000078565"
FT   REGION          643..749
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        643..694
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        707..723
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   749 AA;  84193 MW;  DD6ADD1C0D4E94C3 CRC64;
     MGRVVGIDLG TTNSVIAVME GGKPMVIANA EGVRTTPSVV GVSKTGERLV GELARRQLVL
     NPRNTFANIK RFIGRRYDEL TDESKRVPYT VRRDPEGNVR IVCPQLSREF APEEVAAMIL
     RKLAEEASRY LGEPVTGAVI TVPAYFNDSQ RQATRDAGRI AGLEVKRILN EPTAASLAYG
     LDRRDNQTIL VFDLGGGTFD VSVLKVGNGV FEVKATSGDT QLGGNDFDRR IVDWLAEQFL
     EAEGIDLRRD RQALQRLIEA AEKAKIELSG VSVTDINLPF ITATEDEPKH LETRLTRSEF
     EALCEDLLER MMRPLRRALK DARLQPQDID EVVLVGGSTR MPMVQQLVRS LIGREPNQNV
     NPDEVVAIGA AIQAGILAGE VKDILLLDVT PLSLGLETIG GVMKKLIPRN TAIPVRRSDI
     FSTAENNQTM VEIHILQGER QLAEGNKSLG RFKLTGIPPA PRGVPQVQVS FDIDANGILQ
     VSALDKTTGR EQTVTIQGAS TLSQEEVKRM MKDAELYAQQ DRQLKARIEK RNRAQTLIAQ
     SERRLREISL DFGLYFAESK RRRIESTIRE LKDYLERQDD RGLDLALAEL QDALFDLNQE
     TAARLRDEEG EGFFEPLKQT FASLRGDGNR DFERSWDDRG GDRWDADPWD RSRRSTPSYG
     YDDRRSPVSD PYRGERWVEE QTSMSRREPV RDRNGGNGSV RPEPAPRRGR PTWEEDQPPR
     RDRSSQPPAK PASGRRWNDG WDDDDDEWF