ID   DNAK_ALIB4              Reviewed;         628 AA.
AC   A8EWT6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Abu_2195;
OS   Aliarcobacter butzleri (strain RM4018) (Arcobacter butzleri).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Arcobacteraceae; Aliarcobacter.
OX   NCBI_TaxID=367737;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM4018;
RX   PubMed=18159241; DOI=10.1371/journal.pone.0001358;
RA   Miller W.G., Parker C.T., Rubenfield M., Mendz G.L., Woesten M.M.S.M.,
RA   Ussery D.W., Stolz J.F., Binnewies T.T., Hallin P.F., Wang G., Malek J.A.,
RA   Rogosin A., Stanker L.H., Mandrell R.E.;
RT   "The complete genome sequence and analysis of the Epsilonproteobacterium
RT   Arcobacter butzleri.";
RL   PLoS ONE 2:E1358-E1358(2007).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP000361; ABV68409.1; -; Genomic_DNA.
DR   RefSeq; WP_004511080.1; NC_009850.1.
DR   AlphaFoldDB; A8EWT6; -.
DR   SMR; A8EWT6; -.
DR   STRING; 367737.Abu_2195; -.
DR   EnsemblBacteria; ABV68409; ABV68409; Abu_2195.
DR   GeneID; 56464320; -.
DR   KEGG; abu:Abu_2195; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_7; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000001136; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..628
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000059505"
FT   REGION          595..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         197
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   628 AA;  67497 MW;  CEA1DE3D0BB169A1 CRC64;
     MSKVIGIDLG TTNSCVAVYE NGEAKIIPNK EGKNTTPSIV AYTDKGEVLV GDPAKRQAIT
     NPEKTIYSIK RIMGLMMNEP NAKEAQSKVG YKIVDRNGAA AVEIAGKVYT PQEISAKILG
     KLKADAEEYL GDKVTDAVIT VPAYFNDAQR KATQEAGTIA GLNVLRIINE PTAASLAYGL
     DKKGEEKVLV YDLGGGTFDV TVLEIGDGTF EVLSTDGNAF LGGDDFDNAI IDWLAKEFKD
     ENGFDIKNDK MALQRLKDAA ENAKKELSSA ESTEINLPFI SMGNAGPIHL VKSLTRAKFE
     SMTEKLIDET LDHIKIALKE AGLSKGDIDE IIMVGGSTRL PKANQVVKEF FGKDLNKGVN
     PDEVVAAGAA VQAGVLRGDV KDVLLLDVTP LSLGIETLGG VMTKLIDKGT TIPVKKSQVF
     STADDNQPAV SIHVCQGERE FAKDNKSLGM FELSDIPAAP RGVPQIEVTF DIDANGVLNV
     SAKDKGTGKE NKITISGSSG LSDAEIEKMV AEAEANKEAD AKKKAVIEVR NQADALLHST
     RKTLEENENA ISEDEKKAII DAAADLEETL KDENATKEQI EEKLKTLTDK SHKLAEAMYK
     KEQGEQAGAQ PNQKAKKDDD DVIDAEVE