ID   DNAK_BLOFL              Reviewed;         643 AA.
AC   Q7VQL4;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Bfl114;
OS   Blochmannia floridanus.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=203907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12886019; DOI=10.1073/pnas.1533499100;
RA   Gil R., Silva F.J., Zientz E., Delmotte F., Gonzalez-Candelas F.,
RA   Latorre A., Rausell C., Kamerbeek J., Gadau J., Hoelldobler B.,
RA   van Ham R.C.H.J., Gross R., Moya A.;
RT   "The genome sequence of Blochmannia floridanus: comparative analysis of
RT   reduced genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:9388-9393(2003).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; BX248583; CAD83635.1; -; Genomic_DNA.
DR   RefSeq; WP_011126404.1; NC_005061.1.
DR   AlphaFoldDB; Q7VQL4; -.
DR   SMR; Q7VQL4; -.
DR   STRING; 203907.Bfl114; -.
DR   PRIDE; Q7VQL4; -.
DR   EnsemblBacteria; CAD83635; CAD83635; Bfl114.
DR   KEGG; bfl:Bfl114; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_6; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000002192; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..643
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000078439"
FT   REGION          605..643
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         200
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   643 AA;  70591 MW;  E565BE1A8B48034C CRC64;
     MGKIIGVDLG TTNSCVAIIE SNKPRVLENS EGDRTTPSVV AYTQDGEILV GQPAKRQSVT
     NPKNTLFAIK RLIGRRFQDQ EVQRDVKIMP YKIISSNNGD AWLDIKGQKI APPQISAEIL
     KKMKKTAEDY LGENVTEAVI TVPAYFNDAQ RQATKDAGRI AGLEVKRIIN EPTAAALAYG
     LDKEAHGNRI IAVYDLGGGT FDISIIEIDN VDGEKTFEVL ATNGDTHLGG EDFDSLLINY
     LVEEFKKDQG IDLYNDPLAM QRLKESAEKS KIELSTSQQT DVNLPYITAD STGPKHMNLR
     VTRAKLESLV EDLVNRTLDP LKTALKDANL SVSSVNDVIL VGGQTRMPLV QKKVSEFFNK
     EPRKDVNPDE AVAIGAAVQG GVLSGDVKDV LLLDVTPLSL GIETMGGVMT SLIAKNTTIP
     TKHSQVFSTA EDNQSAVTIH VLQGERKRAS DNKSLGQFNL DGIAPAMRGI PQIEVTFDID
     ADGILHVSAK DKNSGREQKI TIKASSGLNE EEIKKMVQEA EANAESDRKF EELVQIRNQA
     DHLLHSTRKQ LKEVGDRISL DDKNSIEQSL KELELVMKNE NKGDIESKVQ ELIKVSGKLL
     EASSQKYKEK VNDSKSDLNK DKSETDASGD VVDAEFEEIK NKK