ID   DNAK_BLOPB              Reviewed;         637 AA.
AC   Q493S7;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=BPEN_118;
OS   Blochmannia pennsylvanicus (strain BPEN).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=291272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BPEN;
RX   PubMed=16077009; DOI=10.1101/gr.3771305;
RA   Degnan P.H., Lazarus A.B., Wernegreen J.J.;
RT   "Genome sequence of Blochmannia pennsylvanicus indicates parallel
RT   evolutionary trends among bacterial mutualists of insects.";
RL   Genome Res. 15:1023-1033(2005).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000016; AAZ40758.1; -; Genomic_DNA.
DR   RefSeq; WP_011282665.1; NC_007292.1.
DR   AlphaFoldDB; Q493S7; -.
DR   SMR; Q493S7; -.
DR   STRING; 291272.BPEN_118; -.
DR   EnsemblBacteria; AAZ40758; AAZ40758; BPEN_118.
DR   KEGG; bpn:BPEN_118; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_6; -.
DR   OMA; ISIKRHM; -.
DR   BioCyc; CBLO291272:BPEN_RS00575-MON; -.
DR   Proteomes; UP000007794; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..637
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000225941"
FT   REGION          600..637
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        602..623
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         200
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   637 AA;  69839 MW;  33F68AF55302B3C9 CRC64;
     MGKIIGIDLG TTNSCVAIIE GNKPRVLENS EGDRTTPSII AYTQDGEILV GQPAKRQSVT
     NPKNTLFAIK RLIGRRFQDT EVQRDVNIMP YKIISADNGD AWLDVKGQKM APPQVSAEIL
     KKMKKTAEDY LGEQISEAVI TVPAYFNDAQ RQATKDSGRI AGLEVKRIIN EPTAAALAYG
     LDKETRGNRT IAVYDLGGGT FDISIIEIDD VDGEKTFEVL STNGDTHLGG EDFDSLLINY
     LADEFKKDQR INLYNDPLAM QRLKEAAEKA KIELSASHQT DVNLPYITAD NTGPKHMNIR
     VTRAKLESLV EDLVNRTMEP LKVALKDANL SVSNINDVIL VGGQTRMPLV QKKVSEFFRK
     EPRRDVNPDE AVAIGAAVQG GVLSGDVKDV LLLDVTPLSL GIETMGGVMT SLIAKNTTIP
     TKHSQIFSTA EDNQSAVTIH VLQGERKRAS DNKSLGQFNL DGIAAAMRGI PQIEVTFDID
     ADGILHVSAK DKNSGREQKI TIKASSGLNE EEINKMVQEA EANAESDRKF EELVQIRNQA
     DHLLHSTKKQ LTEVGDNISL DDKSAIEGAL KELESVIKKE DKNEIESKIQ SLIKVSGKLL
     EASQKHQEQS KSQSSNSTSD PNGEVVDAEF EEIKNKK