ID   DNAK_CENSY              Reviewed;         656 AA.
AC   A0RZ01;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=CENSYa_1961;
OS   Cenarchaeum symbiosum (strain A).
OC   Archaea; Thaumarchaeota; Cenarchaeales; Cenarchaeaceae; Cenarchaeum.
OX   NCBI_TaxID=414004;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A;
RX   PubMed=17114289; DOI=10.1073/pnas.0608549103;
RA   Hallam S.J., Konstantinidis K.T., Putnam N., Schleper C., Watanabe Y.,
RA   Sugahara J., Preston C., de la Torre J., Richardson P.M., DeLong E.F.;
RT   "Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum
RT   symbiosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:18296-18301(2006).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; DP000238; ABK78568.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0RZ01; -.
DR   SMR; A0RZ01; -.
DR   STRING; 414004.CENSYa_1961; -.
DR   PRIDE; A0RZ01; -.
DR   EnsemblBacteria; ABK78568; ABK78568; CENSYa_1961.
DR   KEGG; csy:CENSYa_1961; -.
DR   PATRIC; fig|414004.10.peg.1795; -.
DR   HOGENOM; CLU_005965_2_4_2; -.
DR   OMA; DKMVLQR; -.
DR   Proteomes; UP000000758; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..656
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000059534"
FT   REGION          590..656
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   656 AA;  68225 MW;  9B3458E673863F3C CRC64;
     MAKVIGIDLG TSNSAAAVVM GGKPTIIPAA EGATVGGKAF PSVVAFSKDG DLLVGEPARR
     QAVTNPENTI MAAKRKMGSE HIFKAGGKDY KPQQISSFIL QKIKKDAEAF VGEPVGQAVI
     TVPAYFDDNQ RQATKDAGTI AGLDVVRIIN EPTAASLAFG LDKSKQDMKI LVFDFGGGTL
     DVTVMEMGGG VFEVMSTSGD TQLGGTDMDK AIIDYIVDDF RKREGVDLSQ DSTALTRVRE
     AAEKAKIELS TVMETDVNLP FISHDSSGPK NLELRLTRAK LEELVGPIID RCRPSIEKAL
     ADAKVSPSDI AKIVMVGGPT RMPAVKKFVS SVTGKESESG VDPMEAVAMG AAIQAGIIAG
     DVTSDIVLLD VTPLTLGIDT LGGVREPLIE RNTTIPTSKS KVFTTAVDNQ TAVTIHVVQG
     ERPMTSDNVS LGSFNLTDLP PAPRGIPQIE VKFDIDANGI INVTAKDLGT QKEAKITIES
     SSKLSKDEIE KLREDAEKFS DEDEKKKGKV ELKNEAESFV YTAEKLINHD LKDKITQEQG
     IKISDGIREV KEALDQDPDI LRPKLDSLKA MVNEITTEMY QQAAAQGAAG GAAGGAAGGA
     AGGAAGDAAG AAGDSTGDAA GAAGGPSEGP AGDAGAGESA GPEPGDDGQP KPGPAA