ID   DNAK_CHLCH              Reviewed;         637 AA.
AC   Q3APD2;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Cag_1893;
OS   Chlorobium chlorochromatii (strain CaD3).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Chlorobium/Pelodictyon group; Chlorobium.
OX   NCBI_TaxID=340177;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CaD3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Chlorobium chlorochromatii CaD3.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP000108; ABB29143.1; -; Genomic_DNA.
DR   RefSeq; WP_011362905.1; NC_007514.1.
DR   AlphaFoldDB; Q3APD2; -.
DR   SMR; Q3APD2; -.
DR   STRING; 340177.Cag_1893; -.
DR   PRIDE; Q3APD2; -.
DR   EnsemblBacteria; ABB29143; ABB29143; Cag_1893.
DR   KEGG; cch:Cag_1893; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_4_10; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..637
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000225950"
FT   REGION          503..525
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          598..637
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        598..623
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         196
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   637 AA;  69037 MW;  1A827FF15A294638 CRC64;
     MGKIIGIDLG TTNSCVAVMQ GSQPTVIENS EGNRTTPSVV GFTKTGDRLV GQAAKRQAIT
     NPKNTIFSIK RFMGRRFDEV GEEKKMAPYE LINDSGEARV KINDKVYSPQ EISAMVLQKM
     KQTAEDFLGE KVTEAVITVP AYFNDAQRQA TKDAGRIAGL EVKRIINEPT AAALAYGLDK
     KNASEKVAVF DLGGGTFDIS ILELGEGVFE VKSTDGDTHL GGDDFDQKII DYIAEEFKKQ
     EGIDLRKDAI TLQRLKEAAE KAKIELSSRS DTEINLPFIT ATQEGPKHLV INLTRAKFEA
     ISADLFNKVL DPCRRAVKNA KIEMREIDEV VLVGGSTRIP KIQALVKEFF GKEPNKSVNP
     DEVVAIGAAI QGGVLKGDVT DVLLLDVTPL SLGIETLGGV MTKLIEANTT IPTKKQEVFS
     TASDNQTSVE VHVLQGERPM AADNKTLGRF HLGDIPPAPR GIPQVEVIFD IDANGILHVS
     AKDKATGKEQ SIRIEASSKL SDAEINKMKD DAKQHADEDK KRKEEIDIKN SADALIFSTE
     KQLTELGEKI PTDKKSALEG SLDKLRDAYK NGTTESIKSA MDDLNSQWNS IASDLYQSGA
     GAAQAQPEAP QNSGSSQSSG GDGAVNAEYE VINDDKK