ID   DNAK_CHLP8              Reviewed;         638 AA.
AC   B3QMB2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Cpar_0645;
OS   Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) (Chlorobium vibrioforme
OS   subsp. thiosulfatophilum).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum.
OX   NCBI_TaxID=517417;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 263 / NCIMB 8327;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Zhao F., Li T., Liu Z., Overmann J.,
RA   Bryant D.A., Richardson P.;
RT   "Complete sequence of Chlorobaculum parvum NCIB 8327.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP001099; ACF11065.1; -; Genomic_DNA.
DR   RefSeq; WP_012501898.1; NC_011027.1.
DR   AlphaFoldDB; B3QMB2; -.
DR   SMR; B3QMB2; -.
DR   STRING; 517417.Cpar_0645; -.
DR   EnsemblBacteria; ACF11065; ACF11065; Cpar_0645.
DR   KEGG; cpc:Cpar_0645; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_10; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000008811; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..638
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000119685"
FT   REGION          592..638
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         196
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   638 AA;  69083 MW;  24FD933EDB56C749 CRC64;
     MGKIIGIDLG TTNSCVAVMQ GTQPTVIENS EGYRTTPSMV AFTKTGERLI GQAAKRQAVT
     NPKNTIFSIK RFMGRKYDEV PNEKKFASYD VVNEGGDARV KIGEKSYSPQ EISAMILQKM
     KQTAEDFLGE KVTEAVITVP AYFNDAQRQA TKDAGKIAGL EVKRIINEPT AAALAYGLDK
     KKENEKVAVF DLGGGTFDIS ILELGDGVFE VKSTDGDTHL GGDDFDQVII DYLADEFKKQ
     EGIDLRKDAI ALQRLKEAAE KAKIELSSRT DTEINLPFIT ATQEGPKHLV INLTRAKFEA
     MSATLFDKVL EPCRRALKNS KLDMKEIDEV VLVGGSSRIP KVQALVKEFF GKEPNKSVNP
     DEVVAIGAAI QGGVLQGDVT DVLLLDVTPL SLGIETLGGV MTKLIEANST IPTRKQETFS
     TAADNQTSVE VHVLQGERPM ASDNKTLGRF HLGDIPPAPR GIPQIEVTFD IDANGILNVS
     AKDKATGKEQ SIKIEASGKL TEAEIEKMKE DAKAHADEDQ KRKEEIDLKN SADSLIFSTE
     KQLSELGDKL PADKKAEIES ALEKLKEAHK AGSADAIKPA MDELSKVWSE AASNLYQQPG
     AEAGAAPQPE TNGQQESKGG DGAVNAEYEV IDGDDDKK