ID   DNAK_CLAM3              Reviewed;         623 AA.
AC   A5CM86;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=CMM_0151;
OS   Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382).
OC   Bacteria; Actinobacteria; Micrococcales; Microbacteriaceae; Clavibacter.
OX   NCBI_TaxID=443906;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCPPB 382;
RX   PubMed=18192381; DOI=10.1128/jb.01595-07;
RA   Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M.,
RA   Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O.,
RA   Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C.,
RA   Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O.,
RA   Bartels D.;
RT   "The genome sequence of the tomato-pathogenic actinomycete Clavibacter
RT   michiganensis subsp. michiganensis NCPPB382 reveals a large island involved
RT   in pathogenicity.";
RL   J. Bacteriol. 190:2138-2149(2008).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; AM711867; CAN00171.1; -; Genomic_DNA.
DR   RefSeq; WP_011931370.1; NC_009480.1.
DR   AlphaFoldDB; A5CM86; -.
DR   SMR; A5CM86; -.
DR   STRING; 443906.CMM_0151; -.
DR   PRIDE; A5CM86; -.
DR   EnsemblBacteria; CAN00171; CAN00171; CMM_0151.
DR   GeneID; 56884429; -.
DR   KEGG; cmi:CMM_0151; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_4_11; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000001564; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 2.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..623
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000059538"
FT   REGION          580..623
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         175
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   623 AA;  67153 MW;  A27CD9F9BBFB8A34 CRC64;
     MARAVGIDLG TTNSVVSVLE GGEPTVIANA EGARTTPSVV AFTKDGEVLV GETAKRQNVT
     NVDRTISSVK RHMGTDWTVG IDDKKYTSQE LSARILGKLK RDAEQYLGDS VTDAVITVPA
     YFNDAERQAT KEAGEIAGLN VLRIINEPTA AALAYGLDRG KEDELILVFD LGGGTFDVSL
     LEVGKDDDFS TIQVRSTAGD NRLGGDDWDQ RIVDHLVKRF KESTGVDVSN DKIAKQRLKE
     AAEQAKKELS SSTSTSIQLP YLSLTENGPA NLDETLTRAK FEELTNDLLE RTRKPFEDVI
     REAGVSVGDV AHVVLVGGST RMPAVVDLVK KLTGGKEPNK GVNPDEVVAV GAALQAGVLK
     GERKDVLLID VTPLSLGIET KGGIMTKLIE RNTAIPTKRS ETFTTADDNQ PSVAIQVFQG
     EREFTRDNKN LGTFELTGIA PAPRGIPQVE VTFDIDANGI VHVSAKDKGT GKEQSMTITG
     GSSLGKEDIE RMVREAEEHA AEDKTRREQA EVRNNAEQLA YSIDKLIKEN DDKLPEDVKS
     EVQGDVDGLK SALAGDDEDA VKTAFDKLSA SQTKLGEAIY AQGQQEQAAG ETPEGASEAK
     KDDEDIVDAE VVDEDDEDKK TDR