ID   DNAK_CORA7              Reviewed;         614 AA.
AC   C3PJM6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=cauri_2321;
OS   Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CIP 107346 /
OS   CN-1) (Corynebacterium nigricans).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=548476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700975 / DSM 44827 / CIP 107346 / CN-1;
RX   PubMed=20137072; DOI=10.1186/1471-2164-11-91;
RA   Trost E., Gotker S., Schneider J., Schneiker-Bekel S., Szczepanowski R.,
RA   Tilker A., Viehoever P., Arnold W., Bekel T., Blom J., Gartemann K.H.,
RA   Linke B., Goesmann A., Puhler A., Shukla S.K., Tauch A.;
RT   "Complete genome sequence and lifestyle of black-pigmented Corynebacterium
RT   aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a
RT   vaginal swab of a woman with spontaneous abortion.";
RL   BMC Genomics 11:91-91(2010).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP001601; ACP33912.1; -; Genomic_DNA.
DR   RefSeq; WP_010188673.1; NZ_ACLH01000047.1.
DR   AlphaFoldDB; C3PJM6; -.
DR   SMR; C3PJM6; -.
DR   STRING; 548476.cauri_2321; -.
DR   PRIDE; C3PJM6; -.
DR   EnsemblBacteria; ACP33912; ACP33912; cauri_2321.
DR   GeneID; 31924969; -.
DR   KEGG; car:cauri_2321; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_4_11; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000002077; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..614
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000133141"
FT   REGION          491..528
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          581..614
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        491..510
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         175
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   614 AA;  65980 MW;  ED04CBD7CA5B5C8A CRC64;
     MGRAVGIDLG TTNSVVSVLE GGEATVIANS EGSRTTPSVV AFAKNGEILV GQSAKNQAVT
     NVDRTIRSVK RHIGTDWTID IDDKKYTPQE ISARTLMKLK RDAEAYLGED VTDAVITVPA
     YFEDSQRQAT KEAGQIAGLN VLRIVNEPTA AALAYGLEKG EQEQTILVFD LGGGTFDVSL
     LEIGDGVVEV MATAGDNALG GDDWDQRIVD WLVDKFKASQ GVDLTKDKRA VQRLREAAEK
     AKIELSSSQS ANINLPYITV DSEKNPLFLD ETLSRTEFQK ITQDLLDRTK TPFNQVIKDA
     GLSLSEVDHV VLVGGSTRMP AVSDLVKEMT GKDPNKGVNP DEVVAVGAAL QAGVLRGEVK
     DVLLLDVTPL SLGIETKGGV MTKLIERNTT IPTKKSETFT TADDNQPSVQ IQVYQGEREM
     ASANKLLGSF ELGGIAPAPR GVPQIEVTFD IDANGIVSVS AKDKATGKEN TIKIQDGSGL
     SQEEIDRMVK DAEAHAEEDK KRREEQETRN QAESTSYQTR KFMDENSDKL PEDLKTRVTE
     AADAVDEALK GDDIEAIKSA VEKLGTESQE LGKALYEAQA AEAGAEGAAA GEAAGDPNVV
     DAEVVDEDDE NKEK