ID   DNAK_DESAL              Reviewed;         639 AA.
AC   B8FGS3;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Dalk_3615;
OS   Desulfatibacillum aliphaticivorans.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfobacterales;
OC   Desulfobacteraceae; Desulfatibacillum.
OX   NCBI_TaxID=218208;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK-01;
RX   PubMed=21651686; DOI=10.1111/j.1462-2920.2011.02516.x;
RA   Callaghan A.V., Morris B.E., Pereira I.A., McInerney M.J., Austin R.N.,
RA   Groves J.T., Kukor J.J., Suflita J.M., Young L.Y., Zylstra G.J., Wawrik B.;
RT   "The genome sequence of Desulfatibacillum alkenivorans AK-01: a blueprint
RT   for anaerobic alkane oxidation.";
RL   Environ. Microbiol. 14:101-113(2012).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP001322; ACL05303.1; -; Genomic_DNA.
DR   RefSeq; WP_015948360.1; NC_011768.1.
DR   AlphaFoldDB; B8FGS3; -.
DR   SMR; B8FGS3; -.
DR   PRIDE; B8FGS3; -.
DR   EnsemblBacteria; ACL05303; ACL05303; Dalk_3615.
DR   KEGG; dal:Dalk_3615; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_3_7; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000000739; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..639
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000119697"
FT   REGION          599..639
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   639 AA;  68026 MW;  FD470020CACD5CE7 CRC64;
     MGKVIGIDLG TTNSCVAVME GKEPKVLTNP DGGRTTPSIV GISSSGERLV GQIAKRQAIT
     NPQNTVFAVK RLIGRKFASQ QVKDDMNVLP YQIVDGDNGD AYIELQGKKY SPQEISSFIL
     AYIKKAAEEY LGETVTDAVI TVPAYFNDSQ RQATKDAGKI AGLNVLRIIN EPTAASLAYG
     LDKKSDEKIA VFDLGGGTFD VSILEIGEGV FEVKSTNGDT HLGGEDFDLL VIDYLADEFK
     KDQGIDLRSD KMALQRLKEA AEKAKMELST SVETEVNLPF ITADASGPKH LNVKLTRAKL
     ESLVSDLLDK LEGPCVTALK DAGMSASEVD EVILVGGMTR MPAVQERVKK IFGKEPHKGV
     NPDEVVAIGA GIQGGVLMGD VKDVLLLDVT PLSLGIETLG GVMTKLIEKN TTIPTKKSQV
     FSTAADNQPA VSIHVLQGER EMATGNKTLG RFELVGIPPA PRGVPQIEVT FDIDANGIVS
     VSAKDQGTGK EQSIKITASS GLTEEEIEQM VKDAELHAEE DKKKKELADA RNNADALVYA
     TEKSLKDLGD KIDASTKENV EAAVEKLKKA LEGEDVEEIK RLSEELTTAS HKLAEAMYQQ
     ASAEGQAGAA GDPGAGQGAA GGAAPDDDVV DADFEEVKD