ID   DNAK_DESOH              Reviewed;         642 AA.
AC   A8ZRW3;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Dole_0070;
OS   Desulfococcus oleovorans (strain DSM 6200 / JCM 39069 / Hxd3).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfobacterales;
OC   Desulfosudaceae; Desulfosudis.
OX   NCBI_TaxID=96561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6200 / JCM 39069 / Hxd3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Wawrik B.,
RA   Richardson P.;
RT   "Complete sequence of Desulfococcus oleovorans Hxd3.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000859; ABW65880.1; -; Genomic_DNA.
DR   RefSeq; WP_012173499.1; NC_009943.1.
DR   AlphaFoldDB; A8ZRW3; -.
DR   SMR; A8ZRW3; -.
DR   STRING; 96561.Dole_0070; -.
DR   PRIDE; A8ZRW3; -.
DR   EnsemblBacteria; ABW65880; ABW65880; Dole_0070.
DR   KEGG; dol:Dole_0070; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_7; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000008561; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..642
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000119699"
FT   REGION          594..642
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   642 AA;  68730 MW;  D978DBA95B6E3367 CRC64;
     MAKTIGIDLG TTNSCVAVME GGEAKVITNP EGGRTTPSIV AINEDGERLV GQVAKRQAIT
     NPENTVFGVK RLIGRKFDSA EVQHDIKVLP YKIEKAGNGD LRINLRDKQY SPAEISSFIL
     ADIKHTAEEY LGEKVTDAVI TVPAYFSDSQ RQATKDAGKI AGLNVLRIIN EPTAASLAYG
     LDKKKDEKIA VFDLGGGTFD ISVLEIGDGV FEVKSTNGDT HLGGEDFDLR VVDYLASEFK
     KDQGIDLRQD KMALQRLKEA AEKAKMELSS SPQTDINLPF ITADANGPKH LNIKLSRAKL
     EELVEDLLDK MAKPCETALK DSGFSASQID EVILVGGMTR MPAVQDRVKK IFGKAPNKSV
     NPDEVVAIGA AIQAGVLQGD VNDVLLLDVT PLSLGIETLG GVMTKLIEKN TTIPTKKSQV
     FSTAADNQPA VSIHVLQGER EMAANNKTLG RFDLADIPAA PRGVPQIEVT FDIDANGIVA
     VSAKDLGTGK EQSIKITASS GLSKEEIDKL VKDAEAHAEE DKNKRELVEA QNTADALIYQ
     TEKSIKELGE DKLDNATKAE IQAKIEELKK AKETTDTDQI KKLSDELTQA SHKLAEAMYQ
     KASQEGQQAS GGDAGASADG GTSSAAGGDD DVIDADYEEA GK