ID   DNAK_DESPS              Reviewed;         633 AA.
AC   Q6AMQ3;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=DP1643;
OS   Desulfotalea psychrophila (strain LSv54 / DSM 12343).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfobacterales;
OC   Desulfocapsaceae; Desulfotalea.
OX   NCBI_TaxID=177439;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12343 / LSv54;
RX   PubMed=15305914; DOI=10.1111/j.1462-2920.2004.00665.x;
RA   Rabus R., Ruepp A., Frickey T., Rattei T., Fartmann B., Stark M., Bauer M.,
RA   Zibat A., Lombardot T., Becker I., Amann J., Gellner K., Teeling H.,
RA   Leuschner W.D., Gloeckner F.-O., Lupas A.N., Amann R., Klenk H.-P.;
RT   "The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from
RT   permanently cold Arctic sediments.";
RL   Environ. Microbiol. 6:887-902(2004).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR522870; CAG36372.1; -; Genomic_DNA.
DR   RefSeq; WP_011188884.1; NC_006138.1.
DR   AlphaFoldDB; Q6AMQ3; -.
DR   SMR; Q6AMQ3; -.
DR   STRING; 177439.DP1643; -.
DR   EnsemblBacteria; CAG36372; CAG36372; DP1643.
DR   KEGG; dps:DP1643; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_7; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000000602; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..633
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000225958"
FT   REGION          599..633
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   633 AA;  68122 MW;  EE59B302B8A0D341 CRC64;
     MGKIIGIDLG TTNSCVSVME GGEPKVIANV EGNRTTPSVV AFADNDERLV GMIAKRQAVT
     NPERTVYAAK RLIGRKFTDA EVQRSQEVSP FDIVEGISGS VAIQVEGHKY RPAEISAMVL
     GKMKQTAEEY LGEEVTEAVV TVPAYFNDSQ RQATKDAGKI AGLDVKRIIN EPTAASLAYG
     LDKKVEEKIA VFDLGGGTFD VSVLEIGDGV FEVKSTNGDT FLGGEDFDMR IVHWLADEFK
     REQGIDLRSD KMALQRLKEE AEKAKMELST TVETDINLPF ITADASGPKH LNIKLSRSKF
     ETLVEDLVER TVGPCKTALK DAGLSASQID EVILVGGMSR MPMVQKKVVE IFGKEPHKGV
     NPDEVVAIGA AIQGGVLQGD VKDVLLLDVT PLSLGIETLG GVTTKLIEKN TTVPTKKSQV
     FSTAADNQPA VSIHVLQGER EMAEGNKTIG RFELADIPTA PRGVPQIEVT FDLDANGILN
     VSAKDMGTGK EQSIKITASS GLTDEEIDRM TKDAELHADE DKKRKELVEA RNSADGLIHS
     TEKTLKDLGD KVDAETKENV EKEIANVKTA LEGDDVEAIK AAIEALTAAS HKLAELMYQQ
     ASQETPGDGD AGAAGAKKKD DDDVVDADYE EVK