ID   DNAK_FLAPJ              Reviewed;         626 AA.
AC   A6GXZ1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=FP0864;
OS   Flavobacterium psychrophilum (strain ATCC 49511 / DSM 21280 / CIP 103535 /
OS   JIP02/86).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=402612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49511 / DSM 21280 / CIP 103535 / JIP02/86;
RX   PubMed=17592475; DOI=10.1038/nbt1313;
RA   Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B.,
RA   Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F.,
RA   Claverol S., Dumetz F., Le Henaff M., Benmansour A.;
RT   "Complete genome sequence of the fish pathogen Flavobacterium
RT   psychrophilum.";
RL   Nat. Biotechnol. 25:763-769(2007).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; AM398681; CAL42964.1; -; Genomic_DNA.
DR   RefSeq; WP_011963020.1; NC_009613.3.
DR   RefSeq; YP_001295780.1; NC_009613.3.
DR   AlphaFoldDB; A6GXZ1; -.
DR   SMR; A6GXZ1; -.
DR   STRING; 402612.FP0864; -.
DR   PRIDE; A6GXZ1; -.
DR   EnsemblBacteria; CAL42964; CAL42964; FP0864.
DR   GeneID; 66552514; -.
DR   KEGG; fps:FP0864; -.
DR   PATRIC; fig|402612.5.peg.879; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_10; -.
DR   OMA; ISIKRHM; -.
DR   Proteomes; UP000006394; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..626
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000059559"
FT   REGION          598..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        598..614
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         197
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   626 AA;  67361 MW;  611055F632DF38B5 CRC64;
     MGKIIGIDLG TTNSCVSVME GQEAVVIPNA EGKRTTPSII AFVEGGEIKV GDPAKRQAVT
     NPTKTVASIK RFMGHSFSET TDEAKRVPYS VVKGDNNTPR VDIDGRLYTA QELSAMTLQK
     MKKTAEDYLG QTVTEAVITV PAYFNDAQRQ ATKEAGEIAG LKVMRIINEP TAAALAYGLD
     KKGIDQKIAV YDLGGGTFDI SILELGDGVF EVLSTNGDTH LGGDDFDQTI IDWLADEFKA
     EEGIDLRLDP MSLQRIKEAA EKAKIELSSS AETEINLPYV TATASGPKHL VKKLTRAKFE
     QLSDTLVKRS MEPVAKALKD AGLTVKDIDE VILVGGSTRM PRIADEVEKF FGKKASKGVN
     PDEVVAIGAA IQGGVLSGDV KDVLLLDVTP LSLGIETMGG VMTILIESNT TIPTKKSQIF
     STAADSQPTV ELHVLQGARA MAVDNKTIGR FNLDGIPPAP RGVPQIEVAF DIDANGIIKV
     SATDKGTGKS HDIRIEASSG LTSEEIERMK KDAEANAGAD KIARERVEKI NEADSLIFQT
     ETQLKELGDK ITDEHKTAIE YALTELRMAH QSQDLEAIQK GLDNVNAAWK TATEAMYAQG
     EQGQAAQPQA ETQGDDVQDV EFEEVK