ID   DNAK_GEOMG              Reviewed;         638 AA.
AC   Q39PT7;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Gmet_3532;
OS   Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=269799;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53774 / DSM 7210 / GS-15;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Geobacter metallireducens GS-15.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP000148; ABB33737.1; -; Genomic_DNA.
DR   RefSeq; WP_004513688.1; NC_007517.1.
DR   AlphaFoldDB; Q39PT7; -.
DR   SMR; Q39PT7; -.
DR   STRING; 269799.Gmet_3532; -.
DR   PRIDE; Q39PT7; -.
DR   EnsemblBacteria; ABB33737; ABB33737; Gmet_3532.
DR   KEGG; gme:Gmet_3532; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_0_7; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000007073; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..638
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000059567"
FT   REGION          600..638
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        617..638
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   638 AA;  68479 MW;  C5392664FD5165D3 CRC64;
     MSKVIGIDLG TTNSCVAIME GGEPVVIANS EGSRTTPSMV AFAESGERLV GQQAKRQAVT
     NPENTLFAIK RLIGRKFDTD EVRKDISISP FKIVKADNGD AWVDVRGKMY SPPEVSAIVL
     QKMKKTAEDY LGETVTDAVI TVPAYFNDSQ RQATKDAGKI AGLNVLRIIN EPTAAALAYG
     LDKKKDEKIA VFDLGGGTFD ISILELGDGV FEVKSTNGDT FLGGEDFDQR VIDWIADEFK
     KDQGIDLRGD KMALQRLKEA AEKAKCELSS SMETDINLPF ITADATGPKH LTMKLSRAKL
     EALCAELLDK LEGPCRTALK DAGLSPSEVD EVILVGGMTR MPAVQKRVQE IFGKAPNKGV
     NPDEVVAIGA GIQGGVLRGD VKDVLLLDVT PLSLGIETLG SVMTKLIDKN TTIPCRKSQV
     FSTASDNQPA VTIHVLQGER EMASDNKTLG NFELTGIPPA PRGVPQIEVT FDIDANGIVH
     VSAKDLGTGK EQSIRITASS GLSKEEIDKM VREAESHAAD DKKKRELIEA RNHADTLAYS
     TEKSLKEYGD KIGDDEKKKI EEAVAALKKA MEGDDVDAIK QATDALTQAS HKLAEAVYAK
     TQTEGGAQPG AEADGDTGAK GGEKVVDADF EEVKDDKK