ID   DNAK_GLAP5              Reviewed;         633 AA.
AC   B8F7S6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=HAPS_1889;
OS   Glaesserella parasuis serovar 5 (strain SH0165) (Haemophilus parasuis).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Glaesserella.
OX   NCBI_TaxID=557723;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SH0165;
RX   PubMed=19074396; DOI=10.1128/jb.01682-08;
RA   Yue M., Yang F., Yang J., Bei W., Cai X., Chen L., Dong J., Zhou R.,
RA   Jin M., Jin Q., Chen H.;
RT   "Complete genome sequence of Haemophilus parasuis SH0165.";
RL   J. Bacteriol. 191:1359-1360(2009).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP001321; ACL33378.1; -; Genomic_DNA.
DR   RefSeq; WP_010787164.1; NC_011852.1.
DR   AlphaFoldDB; B8F7S6; -.
DR   SMR; B8F7S6; -.
DR   STRING; 557723.HAPS_1889; -.
DR   EnsemblBacteria; ACL33378; ACL33378; HAPS_1889.
DR   KEGG; hap:HAPS_1889; -.
DR   PATRIC; fig|557723.8.peg.1873; -.
DR   HOGENOM; CLU_005965_2_1_6; -.
DR   OMA; ISIKRHM; -.
DR   Proteomes; UP000006743; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..633
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000133146"
FT   REGION          600..633
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        600..618
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   633 AA;  68241 MW;  CCA2FBF0A08048BA CRC64;
     MGKIIGIDLG TTNSCVAVMD GDKPRVIENA EGARTTPSII AYTDKETLVG QPAKRQAITN
     PKNTLFAIKR LIGRRFTDSE VQRDIEIMPF EITKADNGDA WVSVKGEKMA PPQISAEVLK
     KMKKTAEDFL GEPVTEAVIT VPAYFSDAQR QATKDAGRIA GLEVKRIINE PTAAALAYGL
     DSKKENQIVA VYDLGGGTFD LSIIEIDNLD GEQTFEVRAT NGDTHLGGED FDNRLINYLV
     EEFQKEQGVD LRNDSMAMQR VKEAAEKAKI ELSSAQSTEV NLPYITADAT GPKHLVLTVT
     RAKLEALVED LVNRSLEPVK VALADAGLSV SEINDVILVG GQTRMPLVQK KVADFFGKEP
     RKDVNPDEAV AIGAAVQGGV LAGDVTDVLL LDVTPLSLGI ETMGGVMTTL IEKNTTIPTK
     KSQVFSTAED NQSAVTIHVL QGERKRASDN KSLGQFNLEG INPAPRGMPQ IEVTFDIDAN
     GIINVSAKDK NTGKEQQIKI QASSGLSDAE IEQMVRDAEA NAEADRKFEE LVQTRNQADA
     IAHSTRKQIA EAGSNLADAD KAKIEEAVAA LEKAAKGEDK ADIEAKIEAL VKASEPLIQA
     GQAQAQQGQQ QAQQSQKDDG VVDAEFEEVK DNK