ID   DNAK_MEGEL              Reviewed;         450 AA.
AC   Q9ZIV1;
DT   25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Chaperone protein DnaK;
DE   AltName: Full=HSP70;
DE   AltName: Full=Heat shock 70 kDa protein;
DE   AltName: Full=Heat shock protein 70;
DE   Flags: Fragment;
GN   Name=dnaK;
OS   Megasphaera elsdenii.
OC   Bacteria; Firmicutes; Negativicutes; Veillonellales; Veillonellaceae;
OC   Megasphaera.
OX   NCBI_TaxID=907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 25940 / DSM 20460 / JCM 1772 / NCIB 8927;
RA   Gupta R.S.;
RT   "The phylogeny of prokaryotes: a new proposal for the classification of
RT   organisms at the highest taxa level integrating phylogenetic and phenotypic
RT   characteristics.";
RL   Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; AF013113; AAC77524.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9ZIV1; -.
DR   SMR; Q9ZIV1; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 2.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..>450
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000078485"
FT   MOD_RES         174
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
FT   NON_TER         450
SQ   SEQUENCE   450 AA;  48067 MW;  2C337D32AA364F68 CRC64;
     MSKVIGIDLG TTNSVVAVME GGEPTVITNT EGSRLTPSVV GFSKTGERLV GQLAKRQAVS
     NPENTISSIK RHMGESYTVD IQGKKYTPQE ISAMILQKLK EDAESYLGEK VTQAVITVPA
     YFNDGQRQAT KDAGKIAGLD VLRIVNEPTA AALAYGLDKG GDGKILVFDL GGGTFDVSIL
     ELGDGVFEVK ATNGNTHLGG DDFDNKVMEW MISEFKKETG IDLSQDKMAE QRLKEAAEKA
     KIELSTVLST NINLPFITAD ATGPKHLDLT LTRAKFNELT EDLVQATMEP TKKAIADSGF
     TIDEIDKIIL VGGSSRIPAV QEAIKSILGK EPSKGVNPDE CVAIGAAIQA GVLVGDVKDV
     LLLDVTPLSL GIETLGGVFT KIIDRNTTIP TSRSQVFSTA VDNQPSVDVH VLQGRREMAA
     DNKTLGRFEL TGIPAAPRGV PRIEVTFNID