ID   DNAK_METAR              Reviewed;         623 AA.
AC   Q0W874;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=UNCMA_27580;
GN   ORFNames=LRC471;
OS   Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=351160;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22066 / NBRC 105507 / MRE50;
RX   PubMed=16857943; DOI=10.1126/science.1127062;
RA   Erkel C., Kube M., Reinhardt R., Liesack W.;
RT   "Genome of rice cluster I archaea -- the key methane producers in the rice
RT   rhizosphere.";
RL   Science 313:370-372(2006).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; AM114193; CAJ35419.1; -; Genomic_DNA.
DR   RefSeq; WP_012037073.1; NC_009464.1.
DR   AlphaFoldDB; Q0W874; -.
DR   SMR; Q0W874; -.
DR   STRING; 351160.LRC471; -.
DR   PRIDE; Q0W874; -.
DR   EnsemblBacteria; CAJ35419; CAJ35419; LRC471.
DR   GeneID; 5143960; -.
DR   KEGG; rci:LRC471; -.
DR   PATRIC; fig|351160.9.peg.2823; -.
DR   eggNOG; arCOG03060; Archaea.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 10764at2157; -.
DR   Proteomes; UP000000663; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..623
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000059694"
FT   REGION          582..623
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        582..606
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   623 AA;  67392 MW;  07868BA7FB23A77E CRC64;
     MSKILGIDLG TSNSEAAIME GGKPVIIPSA EGARMFPSVV AFTKTGERLV GEAARRQAVT
     NPERTIIAIK RKMGTDYKVE IDGKKYTPQE ISAMILQKIK QDAEAYIGEK ITKAVITVPA
     YFNDNQRQAT KDAGTIAGLE VLRVINEPTA AALAFGLDKK GSQKILVFDL GGGTLDVTIM
     EMGDGVFEVL STSGDTQLGG TDMDNKIIDY IASQFKKDTG IDLRNDKMAM QRLRDAAEKA
     KIELSSTLQT QVNLPFITAD ASGPKHLDMM LTRATLEELV REVVERCYAP MRQAISDAKL
     TANQIDRIIL VGGPTRMPII IETIKKFFGK EPERGIDPME CVAMGASIQG GVLAGEVKDL
     LLLDVTPLSL GIETLGNVAT RLIERNTTIP TRKSQVFSTA ADNQTSVEIH VIQGERPMAY
     DNTTLGRFHL IGIPPAPRGI PQIEVTFDID ANGILNVKAK DLGTGKEQAI TITASTKLDK
     SDIERMVKDA EKFAAEDAAK KEKAEVMNQA DTLLYSAEKT LADAGDKITA DQKERVTKGS
     DALREAQKTG DIEKIKAATA DLTKTMNEVA TVLYQAAQQQ YQQQQAAEQA AQQQSGGQQA
     SGSNPGKDPN VVDADYEVVN DKK