ID   DNAK_MYCCT              Reviewed;         591 AA.
AC   Q2SSB0; P0C177; P45958;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Chaperone protein DnaK;
DE   AltName: Full=HSP70;
DE   AltName: Full=Heat shock 70 kDa protein;
DE   AltName: Full=Heat shock protein 70;
GN   Name=dnaK; OrderedLocusNames=MCAP_0369;
OS   Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343
OS   / NCTC 10154).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=340047;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8995799; DOI=10.1099/00207713-47-1-38;
RA   Falah M., Gupta R.S.;
RT   "Phylogenetic analysis of mycoplasmas based on Hsp70 sequences: cloning of
RT   the dnaK (hsp70) gene region of Mycoplasma capricolum.";
RL   Int. J. Syst. Bacteriol. 47:38-45(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=California kid / ATCC 27343 / NCTC 10154;
RA   Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O.,
RA   Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-227.
RX   PubMed=7476192; DOI=10.1111/j.1365-2958.1995.tb02321.x;
RA   Bork P., Ouzounis C., Casari G., Schneider R., Sander C., Dolan M.,
RA   Gilbert W., Gillevet P.M.;
RT   "Exploring the Mycoplasma capricolum genome: a minimal cell reveals its
RT   physiology.";
RL   Mol. Microbiol. 16:955-967(1995).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; U51235; AAB09430.1; -; Genomic_DNA.
DR   EMBL; CP000123; ABC01504.1; -; Genomic_DNA.
DR   EMBL; Z33106; CAA83764.1; -; Genomic_DNA.
DR   PIR; S77870; S77870.
DR   RefSeq; WP_011387254.1; NC_007633.1.
DR   AlphaFoldDB; Q2SSB0; -.
DR   SMR; Q2SSB0; -.
DR   EnsemblBacteria; ABC01504; ABC01504; MCAP_0369.
DR   GeneID; 23778675; -.
DR   KEGG; mcp:MCAP_0369; -.
DR   HOGENOM; CLU_005965_2_4_14; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   PhylomeDB; Q2SSB0; -.
DR   Proteomes; UP000001928; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 2.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..591
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000228608"
FT   REGION          570..591
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        576..591
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         175
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   591 AA;  63869 MW;  B962340066F52343 CRC64;
     MAKEKIIGID LGTTNSVVSV IEGGQPIILE NPEGQRTTPS VVAFKNSDII VGGAAKRQAV
     TNPNVVQSIK SKMGTTSKVN LEGKDYSPEQ ISAEILRYMK NYAEAKLGQK VTKAVITVPA
     YFNDAQRKAT KDAGTIAGLQ VERIINEPTA AALAYGLDKQ DKEETILVYD LGGGTFDVSI
     LAIGGGSFDV IATSGNNKLG GDNFDEEIIK WLLGKIKAEY NIDLSKEKMA LQRLKDEAEK
     AKINLSSQLE VEINLPFIAM NESGPISFAT TLTRSEFNKI TKHLVDLTIQ PVKDALSAAK
     KTPSEINEVL LVGGSTRIPA VQELVKSLLN KEPNRSINPD EVVAMGAAVQ GGVLAGEVTD
     ILLLDVTPLS LGIETMGGVM TKLIERNTTI PAKRTQIFST ATDNQPAVDI NVLQGERAMA
     ADNKSLGQFQ LTGIQPAPRG IPQIEVTFEI DANGIVSVSA KDKNTNEEKT ITISNSGNLS
     EAEVERMIKE AQENAANDEA KKKNIELKNK AENYINIIET SLLQAGDKIS AEQKEQSQKM
     IDEIKELVKN ENYEALEQKM AELEQAMAAA AEFANKHNDS DSNNNSSEQN N