ID   DNAK_MYCGA              Reviewed;         593 AA.
AC   Q7NAU6;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=MYCGA5390;
GN   ORFNames=MGA_0279;
OS   Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
OS   (Mycoplasmoides gallisepticum).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=710127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R(low / passage 15 / clone 2);
RX   PubMed=12949158; DOI=10.1099/mic.0.26427-0;
RA   Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F.,
RA   Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.;
RT   "The complete genome sequence of the avian pathogen Mycoplasma
RT   gallisepticum strain R(low).";
RL   Microbiology 149:2307-2316(2003).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; AE015450; AAP56889.2; -; Genomic_DNA.
DR   RefSeq; WP_011113796.1; NC_004829.2.
DR   AlphaFoldDB; Q7NAU6; -.
DR   SMR; Q7NAU6; -.
DR   PRIDE; Q7NAU6; -.
DR   KEGG; mga:MGA_0279; -.
DR   PATRIC; fig|233150.7.peg.611; -.
DR   HOGENOM; CLU_005965_2_1_14; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000001418; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..593
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000078489"
FT   MOD_RES         181
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   593 AA;  64455 MW;  F817779F346CD3CD CRC64;
     MSNNNGLIIG IDLGTTNSCV SVMEGAQKVV IENPEGKRTT PSVVSYKNGE IIVGDAAKRQ
     MLTNPNTIVS IKRLMGTSKK VKINDKGVEK ELTPEEVSAS ILSYLKDYAE KKTGQKISRA
     VITVPAYFND AERQATKTAG KIAGLTVERI INEPTAAALA YGIDKGHREM KVLVYDLGGG
     TFDVSLLDIA DGTFEVMATA GDNRLGGDDW DNKIIEWIIA EIKKDHPSLD LKSDKMAMQR
     LKEAAERAKI ELSAQLETLI SLPFIAVTPE GPVNAELTLS RAKFEELTKD LLERTRNPIA
     DVLKEAKVDP SQVDEILLVG GSTRMPAVQK LVESMIPNKA PNRTINPDEV VAIGAAVQGG
     VLRGDVKDIL LLDVTPLTLA IETLGGVATP IIKRNTTIPV SKSQIFSTAQ DNQESVDVSI
     YQGERPMARE NKSLGTFSLG GIQPAPKGKP QIEITFNIDA NGILNVKAKD LTTGKENSIT
     ISNSSELDEN EIQRMIRDAE ANKERDAIVK QRIEMRYEGE GIVNTINEIL GSKEAEALPA
     QEKASLTKIV DGINGALKAE KWDELKEQID GFKKWRDDMS KKYGGGEAPA EPK