ID   DNAK_NOVAD              Reviewed;         635 AA.
AC   Q2G6N0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Saro_2054;
OS   Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG
OS   56034 / CIP 105152 / NBRC 16084 / F199).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Novosphingobium.
OX   NCBI_TaxID=279238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 /
RC   F199;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Ivanova N.,
RA   Fredrickson J., Balkwill D., Romine M.F., Richardson P.;
RT   "Complete sequence of Novosphingobium aromaticivorans DSM 12444.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP000248; ABD26493.1; -; Genomic_DNA.
DR   RefSeq; WP_011445702.1; NC_007794.1.
DR   AlphaFoldDB; Q2G6N0; -.
DR   SMR; Q2G6N0; -.
DR   STRING; 279238.Saro_2054; -.
DR   PRIDE; Q2G6N0; -.
DR   EnsemblBacteria; ABD26493; ABD26493; Saro_2054.
DR   KEGG; nar:Saro_2054; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_5; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000009134; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..635
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000059621"
FT   REGION          606..635
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   635 AA;  67999 MW;  012893DC4E290FDA CRC64;
     MAKVIGIDLG TTNSCVAVMD GGTPKVIENS EGARTTPSIV AFTKDGERLI GQPAKRQAVT
     NPDNTIFAVK RLIGRRFDDP MTQKDTELVP YTITKGKNGD AWVKAGGQDY SPSQISAFTL
     QKMKETAEAY LGETVTQAVI TVPAYFNDAQ RQATKDAGQI AGLEVLRIIN EPTAAALAYG
     LDKQDGKTIA VYDLGGGTFD ISILEIGDGV FEVKSTNGDT FLGGEDFDTA VVEYLADKFK
     AKEGMDLKTD KLALQRLKEA AEKAKIELSS AQTTEINLPF ITARMEGGAT TPLHLVETVT
     RADLEKLVAG LIQRTLDPCK KALADAGISA KEIDDVVLVG GMTRMPKVRE VVKDFFGKEP
     HTGVNPDEVV AMGAAIQAGV LQGDVKDVLL LDVTPLSLGI ETLGGIMTKM IDRNTTIPTK
     KSQVYSTAED NQQAVTIRVF QGEREMAQDN KLLGQFDLVG IPPARRGVPQ IEVTFDIDAN
     GIVNVSAKDK GTGKEQQIRI QASGGLSDAD IDQMVRDAEK FAEEDKKRRA AAEAKNNAES
     LIHATERQLE ENGDKVDAGL KAEIEAAIAE AKTAVESGDI DAMNAKAQAL TDKAMKMGQA
     IYEKEQATAA SPGAEAPKAD DDVVDAEFSE VDENK