ID   DNAK_ONYPE              Reviewed;         615 AA.
AC   Q6YPM1;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=PAM_704;
OS   Onion yellows phytoplasma (strain OY-M).
OC   Bacteria; Tenericutes; Mollicutes; Acholeplasmatales; Acholeplasmataceae;
OC   Candidatus Phytoplasma; Candidatus Phytoplasma asteris.
OX   NCBI_TaxID=262768;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OY-M;
RX   PubMed=14661021; DOI=10.1038/ng1277;
RA   Oshima K., Kakizawa S., Nishigawa H., Jung H.-Y., Wei W., Suzuki S.,
RA   Arashida R., Nakata D., Miyata S., Ugaki M., Namba S.;
RT   "Reductive evolution suggested from the complete genome sequence of a
RT   plant-pathogenic phytoplasma.";
RL   Nat. Genet. 36:27-29(2004).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD04789.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AP006628; BAD04789.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q6YPM1; -.
DR   SMR; Q6YPM1; -.
DR   STRING; 262768.PAM_704; -.
DR   EnsemblBacteria; BAD04789; BAD04789; PAM_704.
DR   KEGG; poy:PAM_704; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_4_14; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   BioCyc; OYEL262768:G1G26-857-MON; -.
DR   Proteomes; UP000002523; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..615
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000225988"
FT   REGION          567..615
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        594..615
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         177
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   615 AA;  66958 MW;  5D3E814EE4073CD2 CRC64;
     MTKTNKIIGI DLGTTNSCVA VMEGGEAKVI PNAEGGRTTP SVVSFKGDEI MVGEIAKRQV
     ITNPNTISSI KRHMGEANYT VNVGGKKYTP QEISAMILAN LKKTAEDYLG AQVSEAVITV
     PAYFNDAQRQ ATKDAGKIAG LNVKRIINEP TAAALSYGVD KGDKEQTILV FDLGGGTFDV
     SILTLVDGTF EVLSTSGDNA LGGDDFDLRI VDFLVQEFKK ENSVDLSKDK MAMQRLKDAA
     EKAKKELSGV TSSQISLPFL TMSEAGPLHL EYNMTRAKFN ELTKDLIDRC LAPVKRALGD
     AKLDIEKIDQ VLLVGGSTRI PAVQDLVKNE LKKTPNKSIN PDEVVGIGAA IQGGILSGDV
     KDILTLLDVT PLSLGIETLG NVFTKLIERN STIPTSEKQV FSTAADNLPA VDIHVLQGER
     PLAADNKTLG RFQLTDRPPH RAEFLKLKIT FDLDANGIVS VKAKDLGTNK EQKITISGSG
     ALKEEEIQRM IREAEENAEV DRVKKESIDA RNEAENMIFH TKKSLEDLKA DVTPEEKDKV
     ETQIKELEEA LKGDDTALIK EKTASLTKES QGIAMKAYQK AQEKQAQEKG TQENTTAKNE
     KPQDEVVDAD FEEKK