ID   DNAK_PORGI              Reviewed;         640 AA.
AC   P0C937; Q9ZAD3;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Chaperone protein DnaK;
DE   AltName: Full=HSP70;
DE   AltName: Full=Heat shock 70 kDa protein;
DE   AltName: Full=Heat shock protein 70;
GN   Name=dnaK; OrderedLocusNames=PG_1208;
OS   Porphyromonas gingivalis (strain ATCC BAA-308 / W83).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC   Porphyromonas.
OX   NCBI_TaxID=242619;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-308 / W83;
RX   PubMed=12949112; DOI=10.1128/jb.185.18.5591-5601.2003;
RA   Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E.,
RA   Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L.,
RA   Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J.,
RA   Granger D., Tettelin H., Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E.,
RA   Fraser C.M.;
RT   "Complete genome sequence of the oral pathogenic bacterium Porphyromonas
RT   gingivalis strain W83.";
RL   J. Bacteriol. 185:5591-5601(2003).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; AE015924; AAQ66298.1; -; Genomic_DNA.
DR   RefSeq; WP_004583505.1; NC_002950.2.
DR   AlphaFoldDB; P0C937; -.
DR   SMR; P0C937; -.
DR   STRING; 242619.PG_1208; -.
DR   EnsemblBacteria; AAQ66298; AAQ66298; PG_1208.
DR   KEGG; pgi:PG_1208; -.
DR   PATRIC; fig|242619.8.peg.1119; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_4_10; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   BioCyc; PGIN242619:G1G02-1122-MON; -.
DR   Proteomes; UP000000588; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..640
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000078509"
FT   REGION          600..640
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         197
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   640 AA;  68974 MW;  07CB789EFFFE1EBC CRC64;
     MGKIIGIDLG TTNSCVSVLE GNEPIVITNS EGKRTTPSVV AFVDGGERKV GDPAKRQAIT
     NPTKTIYSIK RFMGETYDQV SREVERVPFK VVRGDNNTPR VDIDGRLYTP QEISAMILQK
     MKKTAEDYLG QEVTEAVITV PAYFNDAQRQ ATKEAGEIAG LKVRRIVNEP TAASLAYGLD
     KSNKDMKIAV FDLGGGTFDI SILELGDGVF EVKSTNGDTH LGGDDFDHVI IDWLAEEFKS
     QEGVDLRQDP MAMQRLKEAA EKAKIELSST SSTEINLPYI MPVNGIPKHL VMTLTRAKFE
     QLADRLIQAC VAPCETALKD AGMSRGDIDE VILVGGSTRI PAIQEIVEKI FGKAPSKGVN
     PDEVVAVGAA IQGGVLTGEV KDVLLLDVTP LSLGIETMGG VMTRLIDANT TIPTKKSEIF
     TTAVDNQPSV EIHVLQGERS LAKDNKSIGR FNLDGIAPAP RQTPQIEVTF DIDANGILNV
     TAHDKATGKK QNIRIEASSG LSDDEIKRMK EEAQANAEAD KKEKERIDKI NQADSMIFQT
     EKQLKELGDK FPADKKAPID TALDKLKEAH KAQDVAAIDT AMAELQTALS AAGEELYKNA
     GAAQGGAQPG PDFGGAQGPS AGDQPSDDKN VTDVDFEEVK