ID   DNAK_PSYA2              Reviewed;         647 AA.
AC   Q4FPS9;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Psyc_2132;
OS   Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Psychrobacter.
OX   NCBI_TaxID=259536;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17307 / VKM B-2377 / 273-4;
RX   PubMed=20154119; DOI=10.1128/aem.02101-09;
RA   Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N.,
RA   Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C.,
RA   Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P.,
RA   Murray A., Thomashow M., Tiedje J.M.;
RT   "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive
RT   Siberian permafrost bacterium, reveals mechanisms for adaptation to low-
RT   temperature growth.";
RL   Appl. Environ. Microbiol. 76:2304-2312(2010).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP000082; AAZ19979.1; -; Genomic_DNA.
DR   RefSeq; WP_011281385.1; NC_007204.1.
DR   AlphaFoldDB; Q4FPS9; -.
DR   SMR; Q4FPS9; -.
DR   STRING; 259536.Psyc_2132; -.
DR   EnsemblBacteria; AAZ19979; AAZ19979; Psyc_2132.
DR   KEGG; par:Psyc_2132; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_6; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000000546; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..647
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000226000"
FT   REGION          605..647
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        612..626
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   647 AA;  69538 MW;  7A30B4E34053A7E7 CRC64;
     MGKVIGIDLG TTNSCVAVME GDKVKIIENA EGTRTTPSIV AYKDDEILVG QSAKRQAVTN
     PNNTLFAIKR LIGRRFDDKV VQKDIGMVPY KIAKADNGDA WVEINGKKLA PPQVSAEILK
     KMKKTAEDYL GEAVTEAVVT VPAYFNDSQR QATKDAGKIA GLDVKRIINE PTAAALAYGM
     DKKQGDSTVA VYDLGGGTFD VSIIEIADVD GEQQFEVLAT NGDTFLGGED FDSALIDFLV
     AEFKKDQDVN LKGDSLAMQR LKEAAEKAKI ELSSAQSTEV NLPYITADSS GPKHLVVTIS
     RSKLESLTEE LVQRTMGPCK MALEDAGIKI GDIDDVILVG GQTRMPLVQQ KVQEFFGQEP
     RKDVNPDEAV AAGAAIQGAV LSGEKTDVLL LDVTPLTLGI ETMGGILTPI IEKNTMIPTK
     KSQVFSTAED NQPAVSIQVY QGERKIANQN KQLGRFDLTD IPPAPRGLPQ IEVSFDINAD
     GIMNISATDK GTGKAQSIQI KADSGLSDEE VEQMIRDAEA NAAEDEKFAN LAQVRNEADG
     RIHAVQKALK DAADKVSDDE KSSVETAISE LEAAAKEDDH DDIKAKLEAL DNAFLPVSQK
     IYADAGAGSE GMDPNQFQQG ADNAGENNQA DDDVVDAEFT EVEDDKK