ID   DNAK_RALSO              Reviewed;         652 AA.
AC   Q8XW40;
DT   19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   19-OCT-2002, sequence version 2.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Chaperone protein DnaK;
DE   AltName: Full=HSP70;
DE   AltName: Full=Heat shock 70 kDa protein;
DE   AltName: Full=Heat shock protein 70;
GN   Name=dnaK; OrderedLocusNames=RSc2635; ORFNames=RS04587;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAD16342.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL646052; CAD16342.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_028853574.1; NC_003295.1.
DR   AlphaFoldDB; Q8XW40; -.
DR   SMR; Q8XW40; -.
DR   STRING; 267608.RSc2635; -.
DR   PRIDE; Q8XW40; -.
DR   EnsemblBacteria; CAD16342; CAD16342; RSc2635.
DR   GeneID; 60502140; -.
DR   KEGG; rso:RSc2635; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_0_4; -.
DR   OMA; ISIKRHM; -.
DR   Proteomes; UP000001436; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..652
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000078522"
FT   REGION          610..652
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         200
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   652 AA;  70104 MW;  889FE53A6A8E10A8 CRC64;
     MGKIIGIDLG TTNSCVSIME GNTPKVIENA EGARTTPSII AYMEDGEILV GAPAKRQAVT
     NPRNTLYAVK RLIGRKFEEK EVQKDIGLMP YTISKADNGD AWVEVRDKKM APPQISAEVL
     RKMKKTAEDY LGEEVTEAVI TVPAYFNDSQ RQATKDAGRI AGLDVKRIIN EPTAAALAFG
     LDKNEKGDRK IAVYDLGGGT FDISIIEIAD VDGEKQFEVL STNGDTFLGG EDFDQRIIDY
     IIGEFKKESG VDLSKDVLAL QRLKDAAEKA KIELSSTQQT EINLPYITAD ASGPKHLNLK
     ITRAKLEALV EDLIARTIEP CRTAIKDAGV KVSDIHDVIL VGGMTRMPKV QEKVKEFFGK
     EARKDVNPDE AVAVGAAIQG QVLGGDRKDV LLLDVTPLSL GIETLGGVMT KMIGKNTTIP
     TKFSQTFSTA DDNQPAVTIK VYQGEREMAS GNKMLGEFNL EGIPPAPRGT PQIEVSFDID
     ANGILHVGAK DKATGKENKI TIKASSGLSE AEIERMVKDA EANAEEDKKL RELVDSRNQG
     EALVHSTRKA LGEYGDKLEA GEKDKIEAAI KDLEDVLKGS DKAAIDAKVE ALATASQKLG
     EKVYADMQAK GGAEAGAEQA AAGAHAGAQA GHGAPQDDNV VDAEFKEVND KK