ID   DNAK_THEYD              Reviewed;         632 AA.
AC   B5YH59;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=THEYE_A1758;
OS   Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87).
OC   Bacteria; Nitrospirae; Thermodesulfovibrionia; Thermodesulfovibrionales;
OC   Thermodesulfovibrionaceae; Thermodesulfovibrio.
OX   NCBI_TaxID=289376;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51303 / DSM 11347 / YP87;
RA   Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.;
RT   "The complete genome sequence of Thermodesulfovibrio yellowstonii strain
RT   ATCC 51303 / DSM 11347 / YP87.";
RL   Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP001147; ACI20675.1; -; Genomic_DNA.
DR   RefSeq; WP_012545409.1; NC_011296.1.
DR   RefSeq; YP_002249549.1; NC_011296.1.
DR   AlphaFoldDB; B5YH59; -.
DR   SMR; B5YH59; -.
DR   STRING; 289376.THEYE_A1758; -.
DR   PRIDE; B5YH59; -.
DR   EnsemblBacteria; ACI20675; ACI20675; THEYE_A1758.
DR   KEGG; tye:THEYE_A1758; -.
DR   PATRIC; fig|289376.4.peg.1714; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_0; -.
DR   InParanoid; B5YH59; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000000718; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..632
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000119770"
FT   REGION          599..632
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        616..632
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   632 AA;  69290 MW;  DAE336984A3DA4F7 CRC64;
     MGKAIGIDLG TTNSVVAVVV GGEPVVIPNQ EGQRTTPSVV AFTDKGERLV GQVAKRQAIT
     NPENTIFSIK RLMGRKYNSQ EVQEAKKRLP YKIVEAPNGD AHVEIMGKRY SPPEISAMIL
     QKLKQAAEDY LGEPVTEAVI TVPAYFDDSQ RQATKDAGRI AGLNVLRIIN EPTAAALAYG
     LDKKKEEKIA VYDLGGGTFD ISILEIGEGV IEVKATNGDT YLGGDDFDIR VMDWLIEEFK
     KQEGIDLRKD RMALQRLKEA AERAKIELSS AMETEINLPF ITADASGPKH LLMKLTRAKL
     EQLVDDLIQK SLEPCKKALS DAGLSQSQID EVILVGGQTR TPKVQKVVQD FFGKEPHKGV
     NPDEVVAVGA AIQAAILKGE VKEVLLLDVT PLSLGIETLG GVFTKIIERN TTIPTKKSQI
     FTTAADNQTA VTIKVYQGER EMAADNKLLG VFELVGIPPA PRGIPQIEVT FDIDANGILH
     VSAKDLATGK EQSIRITASS GLSEEEIKKM IREAEAHAEE DRRKKQIAEA RNEADNMIYT
     VEKTLRDMGD RISEDERKRI EEAIEKCRRI KDTSNDVNEI KAAVEELAKA SHRVAEELYK
     KAGASQQGAG STTQSKKEED VIEAEVEDKD NK