ID   DNAK_TRIL1              Reviewed;         639 AA.
AC   B3E7W9;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000255|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000255|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000255|HAMAP-Rule:MF_00332}; OrderedLocusNames=Glov_2829;
OS   Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) (Geobacter
OS   lovleyi).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Trichlorobacter.
OX   NCBI_TaxID=398767;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1151 / DSM 17278 / SZ;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Tapia R., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Sung Y., Fletcher K.E.,
RA   Ritalahti K.M., Loeffler F.E., Richardson P.;
RT   "Complete sequence of chromosome of Geobacter lovleyi SZ.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000255|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000255|HAMAP-
CC       Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00332}.
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DR   EMBL; CP001089; ACD96542.1; -; Genomic_DNA.
DR   RefSeq; WP_012470871.1; NC_010814.1.
DR   AlphaFoldDB; B3E7W9; -.
DR   SMR; B3E7W9; -.
DR   STRING; 398767.Glov_2829; -.
DR   EnsemblBacteria; ACD96542; ACD96542; Glov_2829.
DR   KEGG; glo:Glov_2829; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_1_7; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   Proteomes; UP000002420; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Reference proteome; Stress response.
FT   CHAIN           1..639
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_1000119709"
FT   REGION          601..639
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        620..639
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00332"
SQ   SEQUENCE   639 AA;  68714 MW;  07F168DB0A232149 CRC64;
     MSKVIGIDLG TTNSCVAIME GGEPIVIANS EGSRTTPSMV AFTEAGERIV GQQAKRQAVT
     NPENTLFAIK RLIGRKFETE AVKKDIAISP FKIVKADNGD AWVDVRDKKY SPPEISAIIL
     QKMKKTAEDY LGETVTDAVI TVPAYFDDSQ RQATKDAGKI AGLNVLRIIN EPTAAALAYG
     LDKKKDEKIA VFDLGGGTFD VSVLELGDGV FEVKSTNGDT FLGGEDFDQK IIDWIADEFK
     KDQGIDLRGD KMALQRLKEA AEKAKCELSG SMETDINLPF ITADASGPKH LNLKLSRAKL
     ESLCDDLLRK LEGPCRTAMK DAGLTASEID EVILVGGMTR MPAVVQRVQE IFGKVPNKGV
     NPDEVVAIGA GIQGGVLKGD VKDVLLLDVT PLSLGIETLG GVLTRLIEKN TTIPCRKSQT
     FSTAADNQPA VSIHVLQGER EMARDNKTLG NFELTGIPPA PRGVPQIEVT FDIDANGIVH
     VSAKDLGTGK EQSIRITASS GLSKEEIDKM VKDAESHAAE DKKKREAIEA RNQADSMIYS
     TEKSLKEVGD KVDAVEKGTI ENKIADLKKV MDSDDAEVIK KATDELAQAA HKLAEAMYAQ
     AQQAPGADSC GGDCGQQQEA GAKPKDEKVV DADFEEVKK