ID   DNAK_TRIV2              Reviewed;         688 AA.
AC   O05714; Q3MEP3;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Chaperone protein DnaK;
DE   AltName: Full=HSP70;
DE   AltName: Full=Heat shock 70 kDa protein;
DE   AltName: Full=Heat shock protein 70;
GN   Name=dnaK; OrderedLocusNames=Ava_0919;
OS   Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Trichormus.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Pohl B., Masepohl B., Spieker R.L., Boehme H.;
RT   "Nucleotide sequence of the dnaK-gene from the heterocyst-forming
RT   cyanobacterium Anabaena variabilis ATCC 29413.";
RL   (er) Plant Gene Register PGR97-097(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29413 / PCC 7937;
RX   PubMed=25197444; DOI=10.4056/sigs.3899418;
RA   Thiel T., Pratte B.S., Zhong J., Goodwin L., Copeland A., Lucas S., Han C.,
RA   Pitluck S., Land M.L., Kyrpides N.C., Woyke T.;
RT   "Complete genome sequence of Anabaena variabilis ATCC 29413.";
RL   Stand. Genomic Sci. 9:562-573(2014).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000250}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; Y13044; CAA73479.1; -; Genomic_DNA.
DR   EMBL; CP000117; ABA20543.1; -; Genomic_DNA.
DR   AlphaFoldDB; O05714; -.
DR   SMR; O05714; -.
DR   STRING; 240292.Ava_0919; -.
DR   PRIDE; O05714; -.
DR   EnsemblBacteria; ABA20543; ABA20543; Ava_0919.
DR   KEGG; ava:Ava_0919; -.
DR   eggNOG; COG0443; Bacteria.
DR   HOGENOM; CLU_005965_2_0_3; -.
DR   OMA; PCQSVNP; -.
DR   Proteomes; UP000002533; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Phosphoprotein;
KW   Stress response.
FT   CHAIN           1..688
FT                   /note="Chaperone protein DnaK"
FT                   /id="PRO_0000078410"
FT   REGION          630..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        630..667
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         198
FT                   /note="Phosphothreonine; by autocatalysis"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   688 AA;  76719 MW;  2CE3C6A0D6C4A425 CRC64;
     MGKVVGIDLG TTNSVVAVME GGKPVVIANA EGMRTTPSVV GFSKDGERVV GQMARRQTVL
     NPQNTFFAVK RYIGRRYNEL SPESKRVPYT IRKDDVGNIK VACPRLNKEF AAEEISAMVL
     KKLADDASAY LGAAVTGAVI TVPAYFNDSQ RQATRDAGRI AGLEVLRILN EPTAASLAYG
     LDRGDTETIL VFDLGGGTFD VSILEVGDGV FEVKATSGDT QLGGNDFDKK IVDWLAEQFL
     ETEGVDLRRD RQALQRLMEA AEKAKIELSA VSITDINLPF ITATEDGPKH LETRLTRSQF
     EGLCADLLGR VRNPVKRALK DAGLRPDDIE EVVLVGGSTR MPMVKQLVRD LIGIEPSENV
     NPDEVVAMGA AIQAGILAGE FKDVLLLDVT PLSLGLEAIG GVMKKLIPRN TTIPVRRSDI
     FSTSENNQNS VEIHVVQGER EMAGDNKSLG RFKLYGIPPA PRGIPQIQVA FDIDANGILQ
     VTALDRTTGR EQSITIQGAS TLSESEVNRM IQEAQKYADV DRERKERVEK RTRSEALILQ
     GERQLREVAL EFGMQFARNR RQRIDNISRE LKESLKENDD RGIDQAYADL QDALYELNRE
     VRQYYAEDED DDLFATIKDI FVGDKDKERD LPRDSYRERD SYNNRDYGRD YGRDYGRDSR
     PSYDSNRPPR KSPRPSYQDN WDDDDDWL