DNAL4_PIG
ID DNAL4_PIG Reviewed; 105 AA.
AC A4F4L4;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 17-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Dynein axonemal light chain 4;
GN Name=DNAL4;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Uhlmann B., Kuiper H., Distl O., Leeb T.;
RT "Molecular characterization of the porcine DNAL4 gene.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Force generating protein of respiratory cilia. Produces force
CC towards the minus ends of microtubules. Dynein has ATPase activity (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Consists of at least two heavy chains and a number of
CC intermediate and light chains. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the dynein light chain family. {ECO:0000305}.
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DR EMBL; AM284969; CAK96013.1; -; Genomic_DNA.
DR RefSeq; NP_001231596.1; NM_001244667.1.
DR RefSeq; NP_001231597.1; NM_001244668.1.
DR AlphaFoldDB; A4F4L4; -.
DR SMR; A4F4L4; -.
DR STRING; 9823.ENSSSCP00000000097; -.
DR PaxDb; A4F4L4; -.
DR PRIDE; A4F4L4; -.
DR Ensembl; ENSSSCT00005017248; ENSSSCP00005010280; ENSSSCG00005011202.
DR Ensembl; ENSSSCT00070053242; ENSSSCP00070045109; ENSSSCG00070026556.
DR Ensembl; ENSSSCT00070053274; ENSSSCP00070045137; ENSSSCG00070026556.
DR GeneID; 100520304; -.
DR KEGG; ssc:100520304; -.
DR CTD; 10126; -.
DR eggNOG; KOG3430; Eukaryota.
DR HOGENOM; CLU_070944_3_0_1; -.
DR InParanoid; A4F4L4; -.
DR OMA; YMFFGGN; -.
DR OrthoDB; 1520814at2759; -.
DR TreeFam; TF324136; -.
DR Reactome; R-SSC-177504; Retrograde neurotrophin signalling.
DR Proteomes; UP000008227; Unplaced.
DR Proteomes; UP000314985; Chromosome 5.
DR Genevisible; A4F4L4; SS.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR Gene3D; 3.30.740.10; -; 1.
DR InterPro; IPR037177; DLC_sf.
DR InterPro; IPR001372; Dynein_light_chain_typ-1/2.
DR PANTHER; PTHR11886; PTHR11886; 1.
DR Pfam; PF01221; Dynein_light; 1.
DR SMART; SM01375; Dynein_light; 1.
DR SUPFAM; SSF54648; SSF54648; 1.
PE 3: Inferred from homology;
KW Cell projection; Cilium; Cytoplasm; Cytoskeleton; Dynein; Microtubule;
KW Motor protein; Reference proteome.
FT CHAIN 1..105
FT /note="Dynein axonemal light chain 4"
FT /id="PRO_0000285676"
SQ SEQUENCE 105 AA; 12009 MW; D0AE8929DEB2AC06 CRC64;
MGETEGKKDE ADYKRLQTFP LVRHSDMPEE MRVETMELCV TACEKFSNNN ESAAKMIKET
MDKKFGSSWH VVIGEGFGFE ITHEVKNLLY LYFGGTLAVC VWKCS