ID   DNAPR_BPT4              Reviewed;         274 AA.
AC   P15076;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 2.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Terminal DNA protecting protein;
DE   AltName: Full=Gene product 64;
DE            Short=gp64;
DE   AltName: Full=Head protein Gp2;
GN   Name=2; Synonyms=64;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2740234; DOI=10.1093/nar/17.11.4392;
RA   Koch T., Lamm N., Rueger W.;
RT   "Sequencing, cloning and overexpression of genes of bacteriophage T4
RT   between map positions 74.325 and 77.184.";
RL   Nucleic Acids Res. 17:4392-4392(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 41-234.
RX   PubMed=2644202; DOI=10.1128/jb.171.1.488-497.1989;
RA   Lipinska B., Rao A.S.M.K., Bolten B.M., Balakrishnan R., Goldberg E.B.;
RT   "Cloning and identification of bacteriophage T4 gene 2 product gp2 and
RT   action of gp2 on infecting DNA in vivo.";
RL   J. Bacteriol. 171:488-497(1989).
RN   [4]
RP   FUNCTION, VIRION, AND SUBCELLULAR LOCATION.
RX   PubMed=10633100; DOI=10.1128/jb.182.3.672-679.2000;
RA   Wang G.R., Vianelli A., Goldberg E.B.;
RT   "Bacteriophage T4 self-assembly: in vitro reconstitution of recombinant gp2
RT   into infectious phage.";
RL   J. Bacteriol. 182:672-679(2000).
CC   -!- FUNCTION: Binds to the viral DNA ends and protects the viral DNA
CC       against recBCD mediated degradation. {ECO:0000269|PubMed:10633100}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:10633100}. Note=Part
CC       of the capsid. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA50418.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X14845; CAA32951.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42438.1; -; Genomic_DNA.
DR   EMBL; M23012; AAA50418.1; ALT_INIT; Genomic_DNA.
DR   PIR; S04610; S04610.
DR   RefSeq; NP_049754.1; NC_000866.4.
DR   GeneID; 1258799; -.
DR   KEGG; vg:1258799; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0099016; P:evasion by virus of DNA end degradation; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   DNA end degradation evasion by virus; Host-virus interaction;
KW   Reference proteome; Virion.
FT   CHAIN           1..274
FT                   /note="Terminal DNA protecting protein"
FT                   /id="PRO_0000164994"
FT   CONFLICT        71..76
FT                   /note="AEKIQK -> VKRFKN (in Ref. 3; AAA50418)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        118
FT                   /note="R -> K (in Ref. 3; AAA50418)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        191
FT                   /note="L -> Q (in Ref. 3; AAA50418)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   274 AA;  31610 MW;  3583A0A76439B3E1 CRC64;
     MAIFQIINES TPQVPKVKQS LNEKKWIQIG LEYKKAKAKG MTGKQFAEER GIKYSTFTSA
     MSKYASGIKT AEKIQKLESK PMNKLNKQER QLLMINSFRQ TLRDKIRNEG AAINNKTRKW
     FAETIKQVKG HKVVRPQPGR IYAFAYDAKH KETLPYWDKF PLIIYLGLGK HNLMYGLNLH
     YIPPKARQQF LEELLKQYAN TPTITNKTKL KIDWSQVKGF RGADQMIKAY IPGNIMGSLV
     EIAPKDWANV VLMPLQQFVS KGKRFSANKV WSNI