ID   DNAT_ECO24              Reviewed;         179 AA.
AC   A7ZVQ2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Primosomal protein 1 {ECO:0000255|HAMAP-Rule:MF_01061};
DE   AltName: Full=Primosomal protein I {ECO:0000255|HAMAP-Rule:MF_01061};
GN   Name=dnaT {ECO:0000255|HAMAP-Rule:MF_01061};
GN   OrderedLocusNames=EcE24377A_4955;
OS   Escherichia coli O139:H28 (strain E24377A / ETEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=331111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E24377A / ETEC;
RX   PubMed=18676672; DOI=10.1128/jb.00619-08;
RA   Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA   Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA   Henderson I.R., Sperandio V., Ravel J.;
RT   "The pangenome structure of Escherichia coli: comparative genomic analysis
RT   of E. coli commensal and pathogenic isolates.";
RL   J. Bacteriol. 190:6881-6893(2008).
CC   -!- FUNCTION: This protein is required for primosome-dependent normal DNA
CC       replication; it is also involved in inducing stable DNA replication
CC       during SOS response. It forms, in concert with DnaB protein and other
CC       prepriming proteins DnaC, N, N', N'' a prepriming protein complex on
CC       the specific site of the template DNA recognized by protein N'.
CC       {ECO:0000255|HAMAP-Rule:MF_01061}.
CC   -!- SIMILARITY: Belongs to the DnaT family. {ECO:0000255|HAMAP-
CC       Rule:MF_01061}.
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DR   EMBL; CP000800; ABV18613.1; -; Genomic_DNA.
DR   RefSeq; WP_000098818.1; NC_009801.1.
DR   AlphaFoldDB; A7ZVQ2; -.
DR   BMRB; A7ZVQ2; -.
DR   SMR; A7ZVQ2; -.
DR   EnsemblBacteria; ABV18613; ABV18613; EcE24377A_4955.
DR   GeneID; 66671752; -.
DR   KEGG; ecw:EcE24377A_4955; -.
DR   HOGENOM; CLU_1501592_0_0_6; -.
DR   OMA; ASFVAYW; -.
DR   Proteomes; UP000001122; Chromosome.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01061; DnaT; 1.
DR   InterPro; IPR020917; DnaT.
DR   InterPro; IPR040480; DnaT_DNA_bind.
DR   Pfam; PF17948; DnaT; 1.
PE   3: Inferred from homology;
KW   DNA replication; Primosome.
FT   CHAIN           1..179
FT                   /note="Primosomal protein 1"
FT                   /id="PRO_1000064461"
FT   REGION          156..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   179 AA;  19455 MW;  8DE048A3B2A6235B CRC64;
     MSSRVLTPDV VGIDALVHDH QTVLAKAEGG VVAVFANNAP AFYAVTPARL AELLALEEKL
     ARPGSDVALD DQLYQEPQAA PVAVPMGKFA MYPDWQPDAD FIRLAALWGV ALREPVTTEE
     LASFIAYWQA EGKVFHHVQW QQKLARSLQI GRASNGGLPK RDVNTVSEPD SQIPPGFRG