DNAT_SALTY
ID DNAT_SALTY Reviewed; 179 AA.
AC P67524; Q8XGA9;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Primosomal protein 1 {ECO:0000255|HAMAP-Rule:MF_01061};
DE AltName: Full=Primosomal protein I {ECO:0000255|HAMAP-Rule:MF_01061};
GN Name=dnaT {ECO:0000255|HAMAP-Rule:MF_01061}; OrderedLocusNames=STM4544;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: This protein is required for primosome-dependent normal DNA
CC replication; it is also involved in inducing stable DNA replication
CC during SOS response. It forms, in concert with DnaB protein and other
CC prepriming proteins DnaC, N, N', N'' a prepriming protein complex on
CC the specific site of the template DNA recognized by protein N'.
CC {ECO:0000255|HAMAP-Rule:MF_01061}.
CC -!- SIMILARITY: Belongs to the DnaT family. {ECO:0000255|HAMAP-
CC Rule:MF_01061}.
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DR EMBL; AE006468; AAL23362.1; -; Genomic_DNA.
DR RefSeq; NP_463403.1; NC_003197.2.
DR RefSeq; WP_000098578.1; NC_003197.2.
DR PDB; 6AEP; X-ray; 1.84 A; A/B=84-179.
DR PDB; 6AEQ; X-ray; 2.25 A; A/B=84-179.
DR PDBsum; 6AEP; -.
DR PDBsum; 6AEQ; -.
DR AlphaFoldDB; P67524; -.
DR SMR; P67524; -.
DR STRING; 99287.STM4544; -.
DR PaxDb; P67524; -.
DR EnsemblBacteria; AAL23362; AAL23362; STM4544.
DR GeneID; 1256070; -.
DR KEGG; stm:STM4544; -.
DR PATRIC; fig|99287.12.peg.4788; -.
DR HOGENOM; CLU_1501592_0_0_6; -.
DR OMA; ASFVAYW; -.
DR PhylomeDB; P67524; -.
DR BioCyc; SENT99287:STM4544-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01061; DnaT; 1.
DR InterPro; IPR020917; DnaT.
DR InterPro; IPR040480; DnaT_DNA_bind.
DR Pfam; PF17948; DnaT; 1.
PE 1: Evidence at protein level;
KW 3D-structure; DNA replication; Primosome; Reference proteome.
FT CHAIN 1..179
FT /note="Primosomal protein 1"
FT /id="PRO_0000199874"
FT REGION 151..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 86..90
FT /evidence="ECO:0007829|PDB:6AEP"
FT HELIX 101..107
FT /evidence="ECO:0007829|PDB:6AEP"
FT HELIX 118..131
FT /evidence="ECO:0007829|PDB:6AEP"
FT HELIX 137..152
FT /evidence="ECO:0007829|PDB:6AEP"
FT HELIX 153..155
FT /evidence="ECO:0007829|PDB:6AEP"
SQ SEQUENCE 179 AA; 19506 MW; 4F7EA618EA2C4435 CRC64;
MSSRILTSDV IGIDVLLHDH HAVLAKSTGG AVAVFANNAP AFYAVTPARM AELLALEEKL
SRPGSDVALD AQFYEEPEAA PVAIPCGKFA MYPAWQPDAD FQRQAALWGV ALREPVTAEE
LAAFIAYWQA EGKVFHHIQW QQKLARSVQI SRSSNGGMPQ RDINSVSEPD NHIPPGFRG
