ID   DNBP_METTH              Reviewed;         111 AA.
AC   O27652;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=DNA-binding protein MTH_1615;
GN   OrderedLocusNames=MTH_1615;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
RN   [2]
RP   STRUCTURE BY NMR OF 32-111.
RX   PubMed=11017201; DOI=10.1038/82823;
RA   Christendat D., Yee A., Dharamsi A., Kluger Y., Savchenko A., Cort J.R.,
RA   Booth V., Mackereth C.D., Saridakis V., Ekiel I., Kozlov G., Maxwell K.L.,
RA   Wu N., McIntosh L.P., Gehring K., Kennedy M.A., Davidson A.R., Pai E.F.,
RA   Gerstein M., Edwards A.M., Arrowsmith C.H.;
RT   "Structural proteomics of an archaeon.";
RL   Nat. Struct. Biol. 7:903-909(2000).
CC   -!- FUNCTION: DNA-binding protein which can interact with a randomly chosen
CC       20-mer of double-stranded DNA.
CC   -!- SIMILARITY: Belongs to the PDCD5 family. {ECO:0000305}.
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DR   EMBL; AE000666; AAB86088.1; -; Genomic_DNA.
DR   PIR; G69082; G69082.
DR   RefSeq; WP_010877223.1; NC_000916.1.
DR   PDB; 1EIJ; NMR; -; A=32-111.
DR   PDBsum; 1EIJ; -.
DR   AlphaFoldDB; O27652; -.
DR   BMRB; O27652; -.
DR   SMR; O27652; -.
DR   STRING; 187420.MTH_1615; -.
DR   EnsemblBacteria; AAB86088; AAB86088; MTH_1615.
DR   GeneID; 24854717; -.
DR   KEGG; mth:MTH_1615; -.
DR   PATRIC; fig|187420.15.peg.1579; -.
DR   HOGENOM; CLU_122978_3_0_2; -.
DR   OMA; KPQFGEQ; -.
DR   EvolutionaryTrace; O27652; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.8.140; -; 1.
DR   HAMAP; MF_00026; dsDNA_bind; 1.
DR   InterPro; IPR022889; DNA_bind_arc.
DR   InterPro; IPR002836; PDCD5-like.
DR   InterPro; IPR036883; PDCD5-like_sf.
DR   PANTHER; PTHR10840; PTHR10840; 1.
DR   Pfam; PF01984; dsDNA_bind; 1.
DR   PIRSF; PIRSF015730; TFAR19; 1.
DR   SUPFAM; SSF46950; SSF46950; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Reference proteome.
FT   CHAIN           1..111
FT                   /note="DNA-binding protein MTH_1615"
FT                   /id="PRO_0000121550"
FT   STRAND          34..36
FT                   /evidence="ECO:0007829|PDB:1EIJ"
FT   HELIX           41..44
FT                   /evidence="ECO:0007829|PDB:1EIJ"
FT   HELIX           50..59
FT                   /evidence="ECO:0007829|PDB:1EIJ"
FT   TURN            60..62
FT                   /evidence="ECO:0007829|PDB:1EIJ"
FT   HELIX           64..79
FT                   /evidence="ECO:0007829|PDB:1EIJ"
FT   HELIX           89..99
FT                   /evidence="ECO:0007829|PDB:1EIJ"
SQ   SEQUENCE   111 AA;  13273 MW;  BE146461E92C893D CRC64;
     MTDLEEIRRK KMLELQQKAQ QQAMEAEAQE QMRQQLEMQK KQIMMQILTP EARSRLANLR
     LTRPDFVEQI ELQLIQLAQM GRVRSKITDE QLKELLKRVA GKKREIKISR K