ID   DNCH_PROMM              Reviewed;         151 AA.
AC   Q7V4A7;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=1,4-dihydroxy-2-naphthoyl-CoA hydrolase {ECO:0000255|HAMAP-Rule:MF_02101};
DE            Short=DHNA-CoA hydrolase {ECO:0000255|HAMAP-Rule:MF_02101};
DE            EC=3.1.2.28 {ECO:0000255|HAMAP-Rule:MF_02101};
DE   AltName: Full=DHNA-CoA thioesterase {ECO:0000255|HAMAP-Rule:MF_02101};
GN   OrderedLocusNames=PMT_2055;
OS   Prochlorococcus marinus (strain MIT 9313).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=74547;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT 9313;
RX   PubMed=12917642; DOI=10.1038/nature01947;
RA   Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A.,
RA   Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L.,
RA   Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C.,
RA   Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R.,
RA   Chisholm S.W.;
RT   "Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche
RT   differentiation.";
RL   Nature 424:1042-1047(2003).
CC   -!- FUNCTION: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA
CC       (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in
CC       phylloquinone (vitamin K1) biosynthesis. {ECO:0000255|HAMAP-
CC       Rule:MF_02101}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-
CC         naphthoate + CoA + H(+); Xref=Rhea:RHEA:26309, ChEBI:CHEBI:11173,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:58897; EC=3.1.2.28; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_02101};
CC   -!- PATHWAY: Cofactor biosynthesis; phylloquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_02101}.
CC   -!- PATHWAY: Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate
CC       biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 7/7.
CC       {ECO:0000255|HAMAP-Rule:MF_02101}.
CC   -!- SIMILARITY: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
CC       DHNA-CoA hydrolase subfamily. {ECO:0000255|HAMAP-Rule:MF_02101}.
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DR   EMBL; BX548175; CAE22229.1; -; Genomic_DNA.
DR   RefSeq; WP_011131420.1; NC_005071.1.
DR   PDB; 2HX5; X-ray; 1.50 A; A=1-151.
DR   PDBsum; 2HX5; -.
DR   AlphaFoldDB; Q7V4A7; -.
DR   SMR; Q7V4A7; -.
DR   STRING; 74547.PMT_2055; -.
DR   DNASU; 1729478; -.
DR   EnsemblBacteria; CAE22229; CAE22229; PMT_2055.
DR   KEGG; pmt:PMT_2055; -.
DR   eggNOG; COG0824; Bacteria.
DR   HOGENOM; CLU_101141_5_3_3; -.
DR   OMA; IVNCEAN; -.
DR   OrthoDB; 1786865at2; -.
DR   UniPathway; UPA00995; -.
DR   UniPathway; UPA01057; UER01033.
DR   EvolutionaryTrace; Q7V4A7; -.
DR   Proteomes; UP000001423; Chromosome.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0042372; P:phylloquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_02101; DHNA_CoA_hydrolase; 1.
DR   InterPro; IPR022829; DHNA_CoA_hydrolase.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   SUPFAM; SSF54637; SSF54637; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Hydrolase; Reference proteome.
FT   CHAIN           1..151
FT                   /note="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
FT                   /id="PRO_0000377022"
FT   ACT_SITE        19
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02101"
FT   HELIX           4..7
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   STRAND          8..12
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   HELIX           15..17
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   STRAND          22..24
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   HELIX           28..44
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   HELIX           48..51
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   STRAND          63..65
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   STRAND          68..75
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   STRAND          84..95
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   STRAND          98..107
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   STRAND          110..120
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   TURN            124..126
FT                   /evidence="ECO:0007829|PDB:2HX5"
FT   HELIX           134..142
FT                   /evidence="ECO:0007829|PDB:2HX5"
SQ   SEQUENCE   151 AA;  17304 MW;  EA9F48E141EBB974 CRC64;
     MNPENWLLLR RVVRFGDTDA AGVMHFHQLF RWCHESWEES LESYGLNPAD IFPGSRKSEV
     TPEVALPIIH CQADFRRPIH TGDALAMELR PERLNPNSFQ VHFEFRCEEQ IAAHALIRHL
     AINAQTRHRC ALPEGIDRWL EASGVGKIGS I